Results 1 to 10 of about 593,691 (360)

Improving the binding affinity and interaction of 5-Pentyl-2-Phenoxyphenol against Mycobacterium Enoyl ACP reductase by computational approach

open access: yesInformatics in Medicine Unlocked, 2021
Tuberculosis (TB) is one of the leading causes of death worldwide. The development of new anti-tubercular drugs is required as resistant strains of M. tuberculosis to various first-line drugs are currently available.
Jakaria Shawon   +3 more
doaj   +1 more source

How the water-soluble hemicarcerand incarcerates guests at room temperature decoded with modular simulations

open access: yesCommunications Chemistry, 2021
Molecular dynamics simulation can reveal conformational dynamics of host-guest complexes, but simulating larger systems can be challenging. Here a modular approach allows simulation of a neocarcerand whose complexation is enabled by the guest-induced ...
Katherine G. McFerrin, Yuan-Ping Pang
doaj   +1 more source

New Method of Degradation Process Identification for Reliability-Centered Maintenance of Energy Equipment

open access: yesEnergies, 2023
Advancements in energy technologies created a new application for gas turbine generators, which are used to balance load. This usage also brought new challenges for maintenance because of harsh operating conditions that make turbines more susceptible to ...
Konstantin Zadiran, Maxim Shcherbakov
doaj   +1 more source

Solving the problem of optimal design for a two-stage reducer by using a modified evolutionary algorithm [PDF]

open access: yesMATEC Web of Conferences, 2020
The work is devoted to solving the problem of selecting optimal geometric parameters of gears of a two-stage cylindrical reducer using a modified evolutionary algorithm (EA).
Ustynenko Oleksandr   +2 more
doaj   +1 more source

An Improved Technique of Hybridization of PSO for the Optimal Coordination of Directional Overcurrent Protection Relays of IEEE Bus System

open access: yesEnergies, 2022
The use of a directional overcurrent protection relay (DOPR) to protect an electrical power system is a crucial instrument for keeping the system dynamic and avoiding undue interruption.
Kashif Habib   +5 more
doaj   +1 more source

Calculation of fatigue fracture in structural elements using a multimode damage model [PDF]

open access: yesMATEC Web of Conferences, 2022
The problem of nucleation and development for the fatigue fracture process in element of aircraft structure is solved using previously developed cyclic damage model.
Nikitin Ilia   +2 more
doaj   +1 more source

STTG-net: a Spatio-temporal network for human motion prediction based on transformer and graph convolution network

open access: yesVisual Computing for Industry, Biomedicine, and Art, 2022
In recent years, human motion prediction has become an active research topic in computer vision. However, owing to the complexity and stochastic nature of human motion, it remains a challenging problem.
Lujing Chen   +5 more
doaj   +1 more source

Design, Synthesis and Biological Evaluation of Brain-Targeted Thiamine Disulfide Prodrugs of Ampakine Compound LCX001

open access: yesMolecules, 2016
Ampakine compounds have been shown to reverse opiate-induced respiratory depression by activation of amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors.
Dian Xiao   +6 more
doaj   +1 more source

VR as a 3D Modelling Tool in Engineering Design Applications

open access: yesApplied Sciences, 2021
The study aims to explore the usefulness of existing VR 3D modelling tools for use in mechanical engineering. Previous studies have investigated the use of VR 3D modelling tools in conceptual phases of the product development process.
Daria Vlah, Vanja Čok, Uroš Urbas
doaj   +1 more source

Determination of critical plane and assessment of fatigue durability for multiaxial cyclic loading and arbitrary shift of phases [PDF]

open access: yesMATEC Web of Conferences, 2019
An analytical solution for the well-known fatigue criterion proposed by Papadopoulos was obtained. An arbitrary shift of phases was taken into account. Comparison between analytical, numerical solutions with experimental data was made.
Stratula Boris A.   +3 more
doaj   +1 more source

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