Results 1 to 10 of about 83,478 (169)

Computer-aided design and Computer-aided engineering [PDF]

open access: yesMATEC Web of Conferences, 2018
In modern industrial production some of the major factors of successful development include: cost reduction of the production, im-provement of its quality, as well as help to minimise the time in market en-try.
Kolbasin Alexander, Husu Oksana
doaj   +2 more sources

How the water-soluble hemicarcerand incarcerates guests at room temperature decoded with modular simulations

open access: yesCommunications Chemistry, 2021
Molecular dynamics simulation can reveal conformational dynamics of host-guest complexes, but simulating larger systems can be challenging. Here a modular approach allows simulation of a neocarcerand whose complexation is enabled by the guest-induced ...
Katherine G. McFerrin, Yuan-Ping Pang
doaj   +1 more source

Improving the binding affinity and interaction of 5-Pentyl-2-Phenoxyphenol against Mycobacterium Enoyl ACP reductase by computational approach

open access: yesInformatics in Medicine Unlocked, 2021
Tuberculosis (TB) is one of the leading causes of death worldwide. The development of new anti-tubercular drugs is required as resistant strains of M. tuberculosis to various first-line drugs are currently available.
Jakaria Shawon   +3 more
doaj   +1 more source

New Method of Degradation Process Identification for Reliability-Centered Maintenance of Energy Equipment

open access: yesEnergies, 2023
Advancements in energy technologies created a new application for gas turbine generators, which are used to balance load. This usage also brought new challenges for maintenance because of harsh operating conditions that make turbines more susceptible to ...
Konstantin Zadiran, Maxim Shcherbakov
doaj   +1 more source

Computer aided ferret design [PDF]

open access: yes2003 International Conference on Geometric Modeling and Graphics, 2003. Proceedings, 2003
In this paper, we explore several extensions to surface pasting. In particular, using the task of modeling a ferret as a driving force, we improved the user interface for cylindrical pasting; we looked at methods for reducing the distortion of pasted features; and we created a method for pasting trimmed features to allow for features that do not have ...
Selina Siu, Stephen Mann
openaire   +1 more source

Computer-Aided Design as Language

open access: yesCoRR, 2021
Computer-Aided Design (CAD) applications are used in manufacturing to model everything from coffee mugs to sports cars. These programs are complex and require years of training and experience to master. A component of all CAD models particularly difficult to make are the highly structured 2D sketches that lie at the heart of every 3D construction.
Yaroslav Ganin   +4 more
openaire   +3 more sources

Solving the problem of optimal design for a two-stage reducer by using a modified evolutionary algorithm [PDF]

open access: yesMATEC Web of Conferences, 2020
The work is devoted to solving the problem of selecting optimal geometric parameters of gears of a two-stage cylindrical reducer using a modified evolutionary algorithm (EA).
Ustynenko Oleksandr   +2 more
doaj   +1 more source

Computer-aided antibody design [PDF]

open access: yesProtein Engineering Design and Selection, 2012
Recent clinical trials using antibodies with low toxicity and high efficiency have raised expectations for the development of next-generation protein therapeutics. However, the process of obtaining therapeutic antibodies remains time consuming and empirical.
Kuroda, Daisuke   +3 more
openaire   +2 more sources

An Improved Technique of Hybridization of PSO for the Optimal Coordination of Directional Overcurrent Protection Relays of IEEE Bus System

open access: yesEnergies, 2022
The use of a directional overcurrent protection relay (DOPR) to protect an electrical power system is a crucial instrument for keeping the system dynamic and avoiding undue interruption.
Kashif Habib   +5 more
doaj   +1 more source

Design, Synthesis and Biological Evaluation of Brain-Targeted Thiamine Disulfide Prodrugs of Ampakine Compound LCX001

open access: yesMolecules, 2016
Ampakine compounds have been shown to reverse opiate-induced respiratory depression by activation of amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors.
Dian Xiao   +6 more
doaj   +1 more source

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