Results 91 to 100 of about 1,561,059 (402)
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Supporting reinterpretation in computer-aided conceptual design [PDF]
, 2008 This paper presents research that aims to inform the development of computational tools that better support design exploration and idea transformation - key objectives in conceptual design.
AHRC (Funder) +7 more
core
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Exploratory Landscape Validation for Bayesian Optimization Algorithms
MathematicsBayesian optimization algorithms are widely used for solving problems with a high computational complexity in terms of objective function evaluation. The efficiency of Bayesian optimization is strongly dependent on the quality of the surrogate models of ...
Taleh Agasiev, Anatoly Karpenko
doaj +1 more source
International Journal of Prosthodontics, 2018 PURPOSE To investigate a computer-aided design/computer-aided manufacturing (CAD/CAM) process for producing one-piece removable partial dentures (RPDs) and to evaluate their fits in vitro.
H. Ye +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Memory Effect in the Spatial Series Based on Diamond and Graphite Crystals
Molecules, 2020 To study the relation between the structure of a compound and its properties is one of the fundamental trends in chemistry and materials science.
Ludmila Grigoreva +4 more
doaj +1 more source
Sliced rotated sphere packing designs [PDF]
arXiv, 2017 Space-filling designs are popular choices for computer experiments. A sliced design is a design that can be partitioned into several subdesigns. We propose a new type of sliced space-filling design called sliced rotated sphere packing designs. Their full designs and subdesigns are rotated sphere packing designs.
arxiv
Universal $p$-ary designs [PDF]
arXiv, 2020 We investigate $p$-ary $t$-designs which are simultaneously designs for all $t$, which we call universal $p$-ary designs. Null universal designs are well understood due to Gordon James via the representation theory of the symmetric group. We study non-null designs and determine necessary and sufficient conditions on the coefficients for such a design ...
arxiv
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source