Results 91 to 100 of about 1,430,083 (395)

A review of computer-aided design/computer-aided manufacture techniques for removable denture fabrication

open access: yesEuropean Journal of Dentistry, 2016
The aim of this review was to investigate usage of computer-aided design/computer-aided manufacture (CAD/CAM) such as milling and rapid prototyping (RP) technologies for removable denture fabrication.
M. Bilgin   +3 more
semanticscholar   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Digitalization of Multi-Object Technological Projecting in Terms of Small Batch Production

open access: yesInventions, 2020
Decreasing the share of time for the technological training of new product creation is an actual and perspective task. The actuality of the given task always increases with the development of machine-building production.
Pavel M. Kuznetsov, Leonid L. Khoroshko
doaj   +1 more source

Modeling and Analysis of Power Processing Systems (MAPPS). Volume 1: Technical report [PDF]

open access: yes
Computer aided design and analysis techniques were applied to power processing equipment. Topics covered include: (1) discrete time domain analysis of switching regulators for performance analysis; (2) design optimization of power converters using ...
Carter, R. A.   +5 more
core   +1 more source

Functional programming for compiling and decompiling computer-aided design

open access: yesProc. ACM Program. Lang., 2018
Desktop-manufacturing techniques like 3D printing are increasingly popular because they reduce the cost and complexity of producing customized objects on demand. Unfortunately, the vibrant communities of early adopters, often referred to as "makers," are
Chandrakana Nandi   +5 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

High-Fidelity 3D-Nanoprinting via Focused Electron Beams: Computer-Aided Design (3BID)

open access: yes, 2018
Currently, there are few techniques that allow true 3D-printing on the nanoscale. The most promising candidate to fill this void is focused electron-beam-induced deposition (FEBID), a resist-free, nanofabrication compatible, direct-write method.
J. Fowlkes   +9 more
semanticscholar   +1 more source

Remineralization potential of nano-hydroxyapatite on enamel and cementum surrounding margin of computer-aided design and computer-aided manufacturing ceramic restoration

open access: yesInternational Journal of Nanomedicine, 2018
Objective This study investigates the effects of nano-hydroxyapatite (NHA) gel and Clinpro (CP) on remineralization potential of enamel and cementum at the cavosurface area of computer-aided design and computer-aided manufacturing ceramic restoration ...
N. Juntavee   +2 more
semanticscholar   +1 more source

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