Results 61 to 70 of about 134,948 (245)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Kriging interpolation over heterogeneous computer architectures and systems

GIScience & Remote Sensing, 2013
Heterogeneous computer architectures are the emerging and future trend in computer engineering but lead to major challenges in algorithm redesign and software re-engineering. This article reviews the evolutional trend in hardware advancement and discusses how to utilize multiple modern graphics processing units (GPUs) and central processing units (CPUs)
Xuan Shi, Fei Ye
openaire   +1 more source

Current Trends in Wildfire Detection, Monitoring and Surveillance

Fire
Wildfires pose severe threats to ecosystems and human settlements, making early detection and rapid response critical for minimizing damage. The adage—“You fight fire in the first second with a spoon of water, in the first minute with a bucket, and in ...
Marin Bugarić, Damir Krstinić, Ljiljana Šerić, Darko Stipaničev   +3 more
doaj   +1 more source

Computational Uses of Philosophical Dialogue Theories

Informal Logic, 1996
The research discussed in this paper concerns an investigation of logical dialogue games as a vehicle for enhanced human-computer communication. The need for a dialogue capability in computer systems is argued, and a prima facie case made for dialogue ...
David Moore, Dave Hobbes
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

RETRIEVAL OF HETEROGENEOUS SERVICES IN C2 NIWA REPOSITORY

TASK Quarterly, 2015
The paper reviews the methods used for retrieval of information and services. The selected approaches presented in the review inspired us to build retrieval mechanisms in a system for searching the resources stored in the C2 NIWA repository. We describe
JULIAN SZYMAŃSKI
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A hardware-software architecture for computer vision systems

ITEGAM-JETIA, 2018
Computer vision systems are based on capture and processing of images, from which information for the application is extracted. This paper presents a hybrid platform which can be easily configured and efficiently used for a large number of applications ...
Antônio Otavio Fernandes, Luiz Fernando E. Moreira, Glauber Tadeu S. Carmo, José M. Mata   +3 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

A NEW OS ARCHITECTURE FOR IOT

Безопасность информационных технологий, 2018
Current computer operating systems architectures are not well suited for the coming world of connected objects, known as the Internet of Things (IoT) for multiple reasons: poor communication performances in both point-to-point and broadcast cases, poor ...
Jean Y. Astier, Igor Y. Zhukov, Oleg N. Murashov, Alexey P. Bardin   +3 more
doaj   +1 more source