Results 31 to 40 of about 3,522,805 (248)

Affect and the computer game player: the effect of gender, personality, and game reinforcement structure on affective responses to computer game-play [PDF]

open access: yes, 2006
Previous research on computer games has tended to concentrate on their more negative effects (e.g., addiction, increased aggression). This study departs from the traditional clinical and social learning explanations for these behavioral phenomena and ...
Chumbley, J, Griffiths, MD
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Investigation of Digital Game Addiction in Elementary School 4th Grade Students According to Sleep and Some Other Variables

open access: yesTürk Uyku Tıbbı Dergisi, 2020
Objective:Digital game addiction negatively affects children’s health and development. Hence, to determine these effects, it is imperative to examine the variables, such as the child’s academic achievement, Body Mass index, sleep, and visual impairment ...
Aslıhan Öztürk Eyimaya   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Computer game playing and social skills: a pilot study [PDF]

open access: yes, 2010
Computer game playing is a popular leisure activity. However, there is little known about the longer-term effects that regular computer game playing could have on social development.
Griffiths, MD
core  

Serious Video Games: Angels or Demons in Patients With Attention-Deficit Hyperactivity Disorder? A Quasi-Systematic Review

open access: yesFrontiers in Psychiatry, 2022
ObjectiveTo carry out a quasi-systematic review of the use of serious video games for health as a cognitive rehabilitative tool in patients diagnosed with attention-deficit hyperactivity disorder.MethodA quasi-systematic review of serious video games ...
María Rodrigo-Yanguas   +9 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Online gaming and addiction: a psychosocial investigation using mixed methods [PDF]

open access: yes, 2010
Online virtual worlds known as Massively Multiplayer Online Role-Playing Games (MMORPGs) have gained increased popularity over the last decade. MMORPGs provide a sophisticated environment that enables complete immersion within the virtual world to the ...
Hussain, Z
core  

The Effect of Cognitive Behavioral Play Therapy Based Psycho-Education Program on the Level of Violent Content Digital Game Addiction and Aggressiveness

open access: yesSakarya University Journal of Education, 2023
Cognitive-behavioral play therapy-based psycho-education program is important because it shows that this type of intervention can reduce levels of violent content digital game addiction and aggressiveness in adolescents.
Tuncay Ayas, Aydın Söylemez
doaj  

Сase study in Russia: the views of parents on schoolchildren’s cyber addiction in the course of online learning

open access: yesCogent Education, 2023
Not only children but also adults now spend much more time in front of the screen (computers, laptops, tablets, phones, TVs, Play Station, other game consoles, etc.) for various reasons: work, study, a lot of free time, communication, entertainment ...
Suad Abdalkareem Alwaely   +3 more
doaj   +1 more source

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