Monovalent derivatives of concanavalin A. [PDF]
Monovalent dimers of concanavalin A (Con A) have been prepared by a combination of succinylation and photoaffinity labeling. Partial derivatization of native Con A using the photoaffinity label, p-azidophenyl-alpha-D-mannopyranoside, followed by affinity chromatography yielded a fraction that consisted of dimers with a single saccharide-binding site at
Andrea Fraser +3 more
openalex +4 more sources
Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis [PDF]
Background In the current period of pharmaceutical discovery, herbal remedies have shown to be an unmatched supply of anticancer medications. Plants and their derivatives, through analogues, play a vital role in cancer treatment.
Gaoyan Hua +3 more
doaj +2 more sources
A Dual-Recognition Electrochemical Sensor Using Bacteria-Imprinted Polymer and Concanavalin A for Sensitive and Selective Detection of Escherichia coli O157:H7 [PDF]
The accurate detection and quantification of pathogenic bacteria is crucial for ensuring public health. In this work, we propose a sensitive and selective sandwich electrochemical sensor for detecting Escherichia coli O157:H7 (E. coli O157:H7).
Xuejie Niu +8 more
doaj +2 more sources
Rose Bengal Conjugated to Lectins for Targeted Antibacterial Photodynamic Treatment [PDF]
Due to rising antibiotic resistance, it is necessary to develop alternative ways to combat pathogenic bacteria. One alternative is photodynamic antibacterial chemotherapy (PACT).
Melad Atrash +3 more
doaj +2 more sources
Comparison of the oxidative respiratory burst and mitogen-induced leukocyte responses of camels, goats, sheep, and cows [PDF]
Background and Aim: The reports from the Ministry of Agriculture and Fisheries suggest that camels suffer less compared to goats, sheep, and cows from a number of common infectious diseases in Oman.
Abeer Al-Hamrashdi +3 more
doaj +1 more source
Polyphosphoramidate Glycohydrogels with Biorecognition Properties and Potential Antibacterial Activity [PDF]
In the present study, for the first time, a biodegradable and non-toxic polyphosphoramidate glycohydrogel (PPAGHGel) was prepared by crosslinking a polyphosphoramidate glycoconjugate (PPAG) with hexamethylene diisocyanate (HMDI) under mild conditions ...
Zornica Todorova +6 more
doaj +2 more sources
Comparison of acute immunological liver injury models in two different species of mice [PDF]
Objective To explore the dose difference on concanavalin A (Con A) induced acute immunological injury of liver in two different species of mice. Methods Thirty six male BALB/C mice and 40 male C57BL/6 mice were randomly divided into 6 groups.BALB/C mice ...
HU Ning, HUANG Hannian, XIA Daozong
doaj +1 more source
Concanavalin A-induced autoimmune hepatitis model in mice: Mechanisms and future outlook
The concanavalin A (Con A)-induced liver injury mouse model is a typical animal model focusing on T cell-dependent hepatic damage in the field of autoimmune hepatitis (AIH).
Liu Yang, Hao Huiqin, Hou Tiezheng
doaj +1 more source
Background & Aims: Aberrant lymphocyte homing could potentially link inflammatory processes in the intestine and the liver, as distinct hepatobiliary diseases frequently develop as extra-intestinal manifestations in inflammatory bowel disease.
Angela Schippers +10 more
doaj +1 more source
The carbon reactions of photosynthesis: role of lectins and glycoregulation
Modulation of glycoregulation in agriculture is reviewed here with emphasis on the elucidation of previously unknown pathways involving vacuolar lectins as well as a bypass of lectins that direct free sugars toward productivity.
A.M. NONOMURA +4 more
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