Buffer 4-Ethylmorpholinium/Acetate: Exploring a New Alternative Buffer for Native Mass Spectrometry. [PDF]
Rapid Commun Mass SpectromABSTRACT Rationale To perform native mass spectrometry (MS) studies, there are a limited number of volatile and electrospray ionization (ESI)‐MS compatible solutions, such as ammonium bicarbonate and ammonium acetate (AA). These solutions could induce the unfolding of proteins due to the formation of CO2 bubbles or induced acidification during ESI ...
Hadavi D +8 more
europepmc +2 more sources
Monovalent derivatives of concanavalin A. [PDF]
Proceedings of the National Academy of Sciences, 1976 Monovalent dimers of concanavalin A (Con A) have been prepared by a combination of succinylation and photoaffinity labeling. Partial derivatization of native Con A using the photoaffinity label, p-azidophenyl-alpha-D-mannopyranoside, followed by affinity chromatography yielded a fraction that consisted of dimers with a single saccharide-binding site at
Andrea Fraser +3 more
openalex +4 more sources
Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis [PDF]
HereditasBackground In the current period of pharmaceutical discovery, herbal remedies have shown to be an unmatched supply of anticancer medications. Plants and their derivatives, through analogues, play a vital role in cancer treatment.
Gaoyan Hua +3 more
doaj +2 more sources
A Dual-Recognition Electrochemical Sensor Using Bacteria-Imprinted Polymer and Concanavalin A for Sensitive and Selective Detection of Escherichia coli O157:H7 [PDF]
FoodsThe accurate detection and quantification of pathogenic bacteria is crucial for ensuring public health. In this work, we propose a sensitive and selective sandwich electrochemical sensor for detecting Escherichia coli O157:H7 (E. coli O157:H7).
Xuejie Niu +8 more
doaj +2 more sources
Rose Bengal Conjugated to Lectins for Targeted Antibacterial Photodynamic Treatment [PDF]
MoleculesDue to rising antibiotic resistance, it is necessary to develop alternative ways to combat pathogenic bacteria. One alternative is photodynamic antibacterial chemotherapy (PACT).
Melad Atrash +3 more
doaj +2 more sources
INTERACTION OF CONCANAVALIN A WITH MODEL SUBSTRATES* [PDF]
Annals of the New York Academy of Sciences, 1974 During the last few years concanavalin A has become the most widely known and intensively investigated phytohemagglutinin. Much of this interest stems from the discovery that this lectin possesses several remarkable biological properties. In addition to its role as a hemagglutinin,' a structural probe,' and a mitogen,"-" concanavalin A has been shown ...
Irwin Goldstein +2 more
openalex +4 more sources
Comparison of the oxidative respiratory burst and mitogen-induced leukocyte responses of camels, goats, sheep, and cows [PDF]
Veterinary World, 2022 Background and Aim: The reports from the Ministry of Agriculture and Fisheries suggest that camels suffer less compared to goats, sheep, and cows from a number of common infectious diseases in Oman.
Abeer Al-Hamrashdi +3 more
doaj +1 more source
Comparison of acute immunological liver injury models in two different species of mice [PDF]
Jichu yixue yu linchuang, 2023 Objective To explore the dose difference on concanavalin A (Con A) induced acute immunological injury of liver in two different species of mice. Methods Thirty six male BALB/C mice and 40 male C57BL/6 mice were randomly divided into 6 groups.BALB/C mice ...
HU Ning, HUANG Hannian, XIA Daozong
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Concanavalin A-induced autoimmune hepatitis model in mice: Mechanisms and future outlook
Open Life Sciences, 2022 The concanavalin A (Con A)-induced liver injury mouse model is a typical animal model focusing on T cell-dependent hepatic damage in the field of autoimmune hepatitis (AIH).
Liu Yang, Hao Huiqin, Hou Tiezheng
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Structural Arrangement Produced by Concanavalin A Binding to Homomeric GluK2 Receptors
Membranes, 2021 Kainate receptors are members of the ionotropic glutamate receptor family. They form cation-specific transmembrane channels upon binding glutamate that desensitize in the continued presence of agonists.
Cuauhtemoc U. Gonzalez +3 more
doaj +1 more source