Results 181 to 190 of about 65,297 (230)
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Biochimica Et Biophysica Acta - General Subjects, 1983
Concanavalin A is capable of activating platelets in a concentration-dependent manner as judged by [14C]serotonin secretion from prelabeled platelets. In contrast, succinyl concanavalin A does not induce platelet secretion. Concanavalin A treatment also results in a number of alterations in platelet macromolecules which are presumably associated with ...
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Concanavalin A is capable of activating platelets in a concentration-dependent manner as judged by [14C]serotonin secretion from prelabeled platelets. In contrast, succinyl concanavalin A does not induce platelet secretion. Concanavalin A treatment also results in a number of alterations in platelet macromolecules which are presumably associated with ...
exaly +3 more sources
Biochemical and Biophysical Research Communications, 1975
Abstract The preparation of monovalent concanavalin A was achieved by incubating metal-free concanavalin A with trypsin at room temperature for 50 hrs. The digest was subjected to affinity chromatography on a column of ovomucoid-agarose to remove the trypsin and subsequent chromatography on Bio-Gel P-150 to resolve the monovalent fragment. Monovalent
D L, Thomasson, R J, Doyle
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Abstract The preparation of monovalent concanavalin A was achieved by incubating metal-free concanavalin A with trypsin at room temperature for 50 hrs. The digest was subjected to affinity chromatography on a column of ovomucoid-agarose to remove the trypsin and subsequent chromatography on Bio-Gel P-150 to resolve the monovalent fragment. Monovalent
D L, Thomasson, R J, Doyle
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Electrokinetic response of granulocytes to concanavalin A and succinyl-concanavalin A
Cell Biophysics, 1981Electrophoretic light scattering has been used to study the effects of concanavalin A (Con A) and succinyl-Con A on the electrophoretic mobility distribution of resident guinea-pig peritoneal eosinophils and human peripheral blood polymorphonuclear leukocytes.
H R, Petty, B R, Ware
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Temperature effects on the concanavalin A molecule and on concanavalin A binding
Biochimica et Biophysica Acta (BBA) - Protein Structure, 1974Abstract Under the same conditions generally used for agglutination tests, the concanavalin A molecule undergoes quarternary structure transitions at different temperatures. The tetrameric form is predominant at 37 °C but it dissociates into dimers as the temperature is lowered.
C, Huet +3 more
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Immunosuppressive Activity of Concanavalin A
Science, 1969Two strains of mice (C-57 B1 and DBA) were given skin allografts from Swiss ICR/HA mice and were treated with varying doses of concanavalin A; the dosage ranged from only two injections of 25 micrograms during the experiment to daily doses of 1000 micrograms intraperitoneally.
H, Markowitz +3 more
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Effect of concanavalin A and succinyl concanavalin A on cytomegalovirus replication in fibroblasts
Archives of Virology, 1986In order to investigate inhibition of viral replication, human embryonic fibroblasts infected with cytomegalovirus (CMV) were treated with 0 to 25 micrograms/ml concanavalin A (Con A) and 0 to 150 micrograms/ml succinylated Con A (S-Con A). Alterations in cellular morphology occurred by day 2 post infection (p.i.) in cultures treated with 10 micrograms/
A, Grail, M, Norval
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Traffic and assembly of concanavalin A
Trends in Biochemical Sciences, 1988Abstract Concanavalin A (ConA) is synthesized and packaged into protein bodies during jackbean development. Recent results have shown that traffic of proteins within the plant cells can be disrupted by monensin, when lectin precursors are mis-routed to the cell surface instead of targeted to their correct intracellular destination.
D J, Bowles, D J, Pappin
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The luminescence properties of concanavalin A
Biochimica et Biophysica Acta (BBA) - Protein Structure, 19751. The luminescence properties of native concanavalin A, both at room temperature and at 77 degrees K, are similar to those of other proteins containing tyrosine and tryptophan. 2. Binding of methyl alpha-D-glucopyranoside to concanavalin A causes a slight reduction of its fluorescence at room temperature. 3.
J N, Miller, G I, Nwokedi
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The interaction of platelets and concanavalin A
Thrombosis Research, 1975Abstract The interaction of agglutinating concanavalin A and non-agglutinating trypsinized concanavalin A preparations with platelet surfaces was monitored by determining the gel electrophoretic labelling pattern of platelet membrane protein obtained from iodinated cells pre-incubated with the plant lectin.
K L, Kaplan, R L, Nachman
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Immunosuppressive Activity of Concanavalin A
International Archives of Allergy and Immunology, 1976Daily intraperitoneal doses of concanavalin A (Con A) produced a dose-related inhibition of adjuvant-induced arthritis in rats. Con A was also effective on established arthritis, markedly relieving the disease after only three doses. The inhibitory effect of Con A was neutralised by pre-incubation with ovalbumin, although this treatment did not modify ...
A K, Delitheos, G B, West
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