Results 191 to 200 of about 65,297 (230)

Concanavalin A: An Introduction

1975
During the last quarter of the nineteenth century and in the beginning of the twentieth century, bacteriologists were searching for agglutinins which could be used as antibacterial agents. Field and Teague (1907), for example, were working with typhoid agglutinins. Kolmer (1923) was working with various other types of antibacterial agglutinins.
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Concanavalin A as a carrier of daunomycin

Nature, 1977
ONE possible approach for increasing the effectiveness of anti-tumour drugs would be to find methods of altering their distribution in the body to increase their local concentration at the tumour cell sites. Ghose et al. have reported the suppression of Ehrlich ascites carcinoma in mice after administration of chlorambucil allegedly bound to anti ...
Kitao, T, Hattori, K
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Agglutination of an Arbovirus by Concanavalin A

Nature New Biology, 1971
MANY enveloped viruses contain carbohydrates as components of glycoproteins1–5 or glycolipid6. We have found (unpublished results) that the envelope of Semliki Forest virus (SFV), a group A arbovirus, contains a glycoprotein in which the principal sugars are mannose, galactose and N-acetylglucos-amine and also a glucose-containing glycolipid.
J D, Oram, D C, Ellwood, G, Appleyard, J L, Stanley   +3 more
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Modification of the Biological Activities of Concanavalin A by Anti-Concanavalin A

1975
Concanavalin A (Con A) bound to cell membrane glycoproteins, may be dissociated from the membrane receptors by competitive ligands such as alpha-methyl-D-mannoside. Addition of antibody to Con A to the system forms complexes of antibody and Con A which are still bound to the membrane receptors.
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Allergenicity of Concanavalin A in Mice

International Archives of Allergy and Immunology, 1979
Concanavalin A (Con A) is a potent allergen in certain strains of mice and in particularly the H-2K^k mice, A/J, CBA/H, and C3H/He. Using a dose of 100 <i>μ</i>g, the subcutaneous route of injection was the most effective means of inducing high, persistent titers of T cell-dependent circulating anti-Con A reagins ...
G F, Mitchell, A E, Clarke
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Effect of Concanavalin A on Phagocytosis

Nature New Biology, 1972
Concanavalin A has been shown to inhibit phagocytosis by polymorphonuclear leucocytes. The effect is reversed by specific sugars.
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Insulinomimetic homology of concanavalin A

Medical Hypotheses, 1983
A striking peptide sequence and three dimensional conformational homology between a portion of insulin and the plant lectin concanavalin A is described. This amino acid sequence has been demonstrated to be essential to the bioactivity of the hormone insulin.
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Structure and Function of Concanavalin A

1975
Lectins have been extensively used to analyze a variety of fundamental processes in cell biology. In conjuntion with our studies on the cell surface and mitosis, we have determined the amino acid sequence and three-dimensional struction of concanavalin A (Con A), the mitogenic lectin from the jack bean.
G N, Reeke, J W, Becker, B A, Cunningham, J L, Wang, I, Yahara, G M, Edelman   +5 more
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The concanavalin a binding properties of concanavalin A-resistant and -sensitive hamster cell lines

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1977
Abstract The binding of labelled concanavalin A to Chinese hamster ovary cells at 4°C exhibits positive cooperativity. Variant cell lines selected for resistance to the cytotoxic effects of the lectin exhibit altered lectin binding properties.
J A, Wright, H, Ceri
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Interactions of concanavalin A with glycoproteins. A quantitative precipitation study of concanavalin A with the soybean agglutinin

Carbohydrate Research, 1991
Certain oligomannose-type glycopeptides have been previously shown to be bivalent for binding to concanavalin A and capable of precipitating the lectin by forming homogeneous cross-linked lattices [L. Bhattacharyya, M. I. Khan, and C.F. Brewer, Biochemistry, 27 (1988) 8762-8767].
M I, Khan, D K, Mandal, C F, Brewer
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