Results 11 to 20 of about 73,159 (258)

Binding of acetylcholinesterases to concanavalin A [PDF]

FEBS Letters, 1974
Acetylcholinesterases from a number of different sources are known to be glycoproteins. Carbohydrate residues were found in the eel enzyme [ 1,2] , human erythrocyte acetylcholinesterase [3 ] torpedo California [4] plaice cholinesterase [ 51 and the cholinesterases from human serum [6,7], horse serum [8,9] and human brain [lo]. It was of interest to us
R. Gentinetta, Therese Wiedmer, Urs Brodbeck   +2 more
openaire   +2 more sources

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

The carbon reactions of photosynthesis: role of lectins and glycoregulation

Photosynthetica, 2020
Modulation of glycoregulation in agriculture is reviewed here with emphasis on the elucidation of previously unknown pathways involving vacuolar lectins as well as a bypass of lectins that direct free sugars toward productivity.
A.M. NONOMURA, D. SHEVELA, S.S. KOMATH, K.Y. BIEL, G. GOVINDJEE   +4 more
doaj   +1 more source

Influence of microbial polyamines on the IL-10 production by peripheral blood leukocytes of healthy donors

Медицинская иммунология, 2023
As is known, bacterial polyamines, which include cadaverine and putrescine, are capable of influencing the activity of immunocompetent cells in many ways.
А. Р. Godovalov, I. А. Morozov
doaj   +1 more source

Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A [PDF]

Brazilian Journal of Medical and Biological Research, 2014
Immune response plays an important role in the development of hepatic fibrosis. In the present study, we investigated the effects of quercetin on hepatitis and hepatic fibrosis induced by immunological mechanism.
Y. Wan, M.H. Tang, X.C. Chen, L.J. Chen, Y.Q. Wei, Y.S. Wang   +5 more
doaj   +3 more sources

Thymoquinone Attenuates Immune Mediated Liver Injury Induced by Concanavalin A in Mice

Iraqi Journal of Pharmaceutical Sciences, 2021
Autoimmune hepatitis is an inflammatory disease and its incidence has been increasing. The features of hepatitis are the release of inflammatory cytokines, the elevation of AST and ALT, and hepatocyte apoptosis and necrosis.
Halla A. Ahmad, Sarmed H. Kathem
doaj   +1 more source

Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization

Frontiers in Immunology, 2022
Immune-mediated hepatic injury plays a key role in the initiation and pathogenesis of diverse liver diseases. However, treatment choice for immune-mediated hepatic injury remains limited.
Fenglian Yan, Fenglian Yan, Dalei Cheng, Dalei Cheng, Haiyan Wang, Haiyan Wang, Min Gao, Junfeng Zhang, Junfeng Zhang, Hongyan Cheng, Hongyan Cheng, Changying Wang, Changying Wang, Hui Zhang, Hui Zhang, Huabao Xiong, Huabao Xiong   +16 more
doaj   +1 more source

CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response

Frontiers in Pharmacology, 2022
Hepatitis is a complex multifactorial pathological disorder, which can eventually lead to liver failure and even potentially be life threatening. Paeoniflorin-6′-O-benzene sulfonate (CP-25) has proven to have critical anti-inflammatory effects in ...
Nan Li, Jing-Jing Wu, Jing-Jing Wu, Meng Qi, Zi-Ying Wang, Sheng-Nan Zhang, Xiu-Qin Li, Ting-Ting Chen, Mei-Fang Wang, Ling-Ling Zhang, Wei Wei, Wu-Yi Sun   +11 more
doaj   +1 more source

Conformational Changes in Concanavalin A [PDF]

Journal of Biological Chemistry, 1971
Abstract The circular dichroic spectrum of homogeneous concanavalin A shows changes in the near ultraviolet upon specific binding of α-methyl-d-mannoside. The far ultraviolet spectrum shows no evidence of α helical structure but most closely resembles the spectrum of the model for type II-β structure, poly-S-carboxymethyl-l-cysteine.
Gerald M. Edelman, Mollie N. Pflumm, John L. Wang   +2 more
openaire   +2 more sources

Differences in the signaling pathways of α1A- and α1B-adrenoceptors are related to different endosomal targeting [PDF]

, 2013
Aims: To compare the constitutive and agonist-dependent endosomal trafficking of α1A- and α1B-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype.
A Hirasawa, AC Hanyaloglu, AL Lattion, B Lei, BL Wolfe, C Moyano, C Stenbergen, CD Wright, D Calebiro, D Chalothorn, D Diviani, D Gesty-Palmer, D Wu, DM Perez, DP Morris, DP Morris, E Oliver, EJ Adie, EJ Adie, Elena Carceller, F Liu, Fermí Montó, Graeme Milligan, Ian Christie McGrath, James Porter, JB Morris, JD Pediani, JD Pediani, JL Benovic, John Pediani, KA DeFea, L Stanasila, LM Luttrell, M von Zastrow, María Antonia Noguera, MC Lyssand JS De Fino, Miguel Pérez-Aso, MW Lee, MY Tsang, P Lajoie, PA Patel, Pilar D’Ocon, RH Oakley, RR Price, S Ahn, S Alexander, S Keffel, S Mhaouty-Kodja, S Terrillon, SK Shenoy, SM DeWire, SS Ferguson, TL Theroux, Vanessa Segura, Y Huang   +54 more
core   +6 more sources