Results 11 to 20 of about 74,223 (272)

GCI-Based Affinity Screening of Synthetic Oligomannosides toward Concanavalin A. [PDF]

open access: yesChemistry
This study describes the development of a reliable GCI method for the affinity determination of neo‐glycoproteins toward concanavalin A (ConA), a model lectin. The final goal is to investigate multivalent carbohydrate–lectin interactions. Abstract Herein, we report the first application of grating‐coupled interferometry (GCI) to quantify the binding ...
Rubes D   +9 more
europepmc   +2 more sources

Influence of microbial polyamines on the IL-10 production by peripheral blood leukocytes of healthy donors

open access: yesМедицинская иммунология, 2023
As is known, bacterial polyamines, which include cadaverine and putrescine, are capable of influencing the activity of immunocompetent cells in many ways.
А. Р. Godovalov, I. А. Morozov
doaj   +1 more source

Binding of acetylcholinesterases to concanavalin A [PDF]

open access: yesFEBS Letters, 1974
Acetylcholinesterases from a number of different sources are known to be glycoproteins. Carbohydrate residues were found in the eel enzyme [ 1,2] , human erythrocyte acetylcholinesterase [3 ] torpedo California [4] plaice cholinesterase [ 51 and the cholinesterases from human serum [6,7], horse serum [8,9] and human brain [lo]. It was of interest to us
R. Gentinetta   +2 more
openaire   +2 more sources

Structural Arrangement Produced by Concanavalin A Binding to Homomeric GluK2 Receptors

open access: yesMembranes, 2021
Kainate receptors are members of the ionotropic glutamate receptor family. They form cation-specific transmembrane channels upon binding glutamate that desensitize in the continued presence of agonists.
Cuauhtemoc U. Gonzalez   +3 more
doaj   +1 more source

Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2014
Immune response plays an important role in the development of hepatic fibrosis. In the present study, we investigated the effects of quercetin on hepatitis and hepatic fibrosis induced by immunological mechanism.
Y. Wan   +5 more
doaj   +3 more sources

Thymoquinone Attenuates Immune Mediated Liver Injury Induced by Concanavalin A in Mice

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
Autoimmune hepatitis is an inflammatory disease and its incidence has been increasing. The features of hepatitis are the release of inflammatory cytokines, the elevation of AST and ALT, and hepatocyte apoptosis and necrosis.
Halla A. Ahmad, Sarmed H. Kathem
doaj   +1 more source

Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization

open access: yesFrontiers in Immunology, 2022
Immune-mediated hepatic injury plays a key role in the initiation and pathogenesis of diverse liver diseases. However, treatment choice for immune-mediated hepatic injury remains limited.
Fenglian Yan   +16 more
doaj   +1 more source

Conformational Changes in Concanavalin A [PDF]

open access: yesJournal of Biological Chemistry, 1971
Abstract The circular dichroic spectrum of homogeneous concanavalin A shows changes in the near ultraviolet upon specific binding of α-methyl-d-mannoside. The far ultraviolet spectrum shows no evidence of α helical structure but most closely resembles the spectrum of the model for type II-β structure, poly-S-carboxymethyl-l-cysteine.
Gerald M. Edelman   +2 more
openaire   +2 more sources

CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response

open access: yesFrontiers in Pharmacology, 2022
Hepatitis is a complex multifactorial pathological disorder, which can eventually lead to liver failure and even potentially be life threatening. Paeoniflorin-6′-O-benzene sulfonate (CP-25) has proven to have critical anti-inflammatory effects in ...
Nan Li   +11 more
doaj   +1 more source

Reversibility of cell surface label rearrangement [PDF]

open access: yes, 1976
Cell surface labeling can cause rearrangements of randomly distributed membrane components. Removal of the label bound to the cell surface allows the membrane components to return to their original random distribution, demonstrating that label is ...
Brown, Susan Smith, Revel, Jean-Paul
core   +1 more source

Home - About - Disclaimer - Privacy