Results 11 to 20 of about 22,621,819 (277)

Thymoquinone Attenuates Immune Mediated Liver Injury Induced by Concanavalin A in Mice

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
Autoimmune hepatitis is an inflammatory disease and its incidence has been increasing. The features of hepatitis are the release of inflammatory cytokines, the elevation of AST and ALT, and hepatocyte apoptosis and necrosis.
Halla A. Ahmad, Sarmed H. Kathem
doaj   +2 more sources

Concanavalin A as a promising lectin-based anti-cancer agent: the molecular mechanisms and therapeutic potential

open access: yesCell Communication and Signaling, 2022
Concanavalin A (ConA), the most studied plant lectin, has been known as a potent anti-neoplastic agent for a long time. Since initial reports on its capacity to kill cancer cells, much attention has been devoted to unveiling the lectin's exact molecular ...
Huldani Huldani   +10 more
doaj   +2 more sources

Concanavalin-A shows synergistic cytotoxicity with tamoxifen via inducing apoptosis in estrogen receptor-positive breast cancer: In vitro and molecular docking studies

open access: yesPharmaceutical Sciences, 2021
Background: Tamoxifen (TAM) is the main treatment of estrogen receptor (ER)-positive breast cancer, however; its adverse effects and development of resistance hinder its use.
Mohamed Elshal   +4 more
semanticscholar   +1 more source

The carbon reactions of photosynthesis: role of lectins and glycoregulation

open access: yesPhotosynthetica, 2020
Modulation of glycoregulation in agriculture is reviewed here with emphasis on the elucidation of previously unknown pathways involving vacuolar lectins as well as a bypass of lectins that direct free sugars toward productivity.
A.M. NONOMURA   +4 more
doaj   +1 more source

Binding of acetylcholinesterases to concanavalin A [PDF]

open access: yesFEBS Letters, 1974
Acetylcholinesterases from a number of different sources are known to be glycoproteins. Carbohydrate residues were found in the eel enzyme [ 1,2] , human erythrocyte acetylcholinesterase [3 ] torpedo California [4] plaice cholinesterase [ 51 and the cholinesterases from human serum [6,7], horse serum [8,9] and human brain [lo]. It was of interest to us
R. Gentinetta   +2 more
openaire   +2 more sources

Concanavalin A

open access: yesDefinitions, 2020
A mannose-binding lectin originally isolated from jack-bean, Canavalia ensiformis. Concanavalin A is a potent lymphocyte mitogen and a stimulator of matrix metalloproteinases, thereby exhibiting immunostimulatory effects.

semanticscholar   +1 more source

Influence of microbial polyamines on the IL-10 production by peripheral blood leukocytes of healthy donors

open access: yesМедицинская иммунология, 2023
As is known, bacterial polyamines, which include cadaverine and putrescine, are capable of influencing the activity of immunocompetent cells in many ways.
А. Р. Godovalov, I. А. Morozov
doaj   +1 more source

Pregabalin inhibits in vivo and in vitro cytokine secretion and attenuates spleen inflammation in Lipopolysaccharide/Concanavalin A -induced murine models of inflammation

open access: yesScientific Reports, 2020
Immune system alteration has been implicated in the pathogenesis of chronic pain conditions, epilepsy and generalized anxiety disorder. Targeting cytokines has recently been proposed for the management of such conditions.
Eman Y. Abu-rish   +5 more
semanticscholar   +1 more source

Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2014
Immune response plays an important role in the development of hepatic fibrosis. In the present study, we investigated the effects of quercetin on hepatitis and hepatic fibrosis induced by immunological mechanism.
Y. Wan   +5 more
doaj   +3 more sources

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