Results 31 to 40 of about 22,621,819 (277)

New Insight into the Concanavalin A-Induced Apoptosis in Hepatocyte of an Animal Model: Possible Involvement of Caspase-Independent Pathway

Molecules, 2023
Concanavalin A (Con A) is known to be a T-cell mitogen and has been shown to induce hepatitis in mice through the triggering of conventional T cells and NKT cells.
Xiangli Zhao, Cheng Fu, Lingjuan Sun, Hao Feng, Peiling Xie, Meng Wu, Xiaosheng Tan, Gang Chen   +7 more
doaj   +1 more source

Immunosuppressive effect of mesenchymal stem cell-derived exosomes on a concanavalin A-induced liver injury model

Inflammation and Regeneration, 2016
This study aimed to evaluate the effect of mesenchymal stem cell (MSC)-derived exosomes on an immune-induced liver injury model. MSCs show a unique function to modulate immune reaction although the molecular mechanisms are still under investigation ...
R. Tamura, S. Uemoto, Y. Tabata
semanticscholar   +1 more source

RIPK1 protects from TNF-α-mediated liver damage during hepatitis [PDF]

, 2016
Cell death of hepatocytes is a prominent characteristic in the pathogenesis of liver disease, while hepatolysis is a starting point of inflammation in hepatitis and loss of hepatic function.
Bertin, John, Bertrand, Mathieu, Dimanche-Boitrel, Marie-Thérèse, Farooq, Muhammad, Filliol, Aveline, Genet, Valentine, Gough, Peter J, Le Seyec, Jacques, Lucas-Clerc, Catherine, Piquet-Pellorce, Claire, Samson, Michel, Vandenabeele, Peter   +11 more
core   +1 more source

MULTIPLEX EVALUATION OF ConA-INDUCED PRODUCTION OF TWELVE CYTOKINES IN THE CULTURES OF MONONUCLEAR CELLS FROM PERIPHERAL BLOOD OF HEALTHY SUBJECTS

Медицинская иммунология, 2014
. The goal of this work was a multiplex single-step evaluation of the levels of stimulated cytokine production in the supernates of cultivated mononuclear cells from healthy Caucasian individuals.
V. I. Konenkov, V. V. Avdoshina, I. G. Rakova, M. V. Smolninkova, E. L. Gelfgat   +4 more
doaj   +1 more source

Construction and function analysis of the LncRNA-miRNA-mRNA competing endogenous RNA network in autoimmune hepatitis

BMC Medical Genomics, 2022
Research Highlights It was the first time to explore the disorder of ceRNA network involved in the pathogenesis of AIH. The co-expression relationship between the differentially expressed lncRNAs, miRNAs and mRNAs were predicted. The potential biological
Zhencheng Li, Ying Liu, Yiwen Hou, Zhurong Li, Chen Chen, Huiqin Hao, Yang Liu   +6 more
doaj   +1 more source

Resolvin D1 and E1 alleviate the progress of hepatitis toward liver cancer in long-term concanavalin A-induced mice through inhibition of NF-κB activity.

Oncology Report, 2016
Resolvins, an endogenous lipid mediator derived from eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) of fish oil, has been reported to have anti-inflammatory and antitumor effect in various pathogenic processes.
Haoyu Kuang, Xiaoli Hua, Jianhui Zhou, Rui Yang   +3 more
semanticscholar   +1 more source

Concanavalin A-Binding Enzymes of Crotalus scutulatus scutulatus Venom [PDF]

, 1985
Crotalus scutulatus scutulatus crude venom was separated into two fractions by Concanavalin A Sepharose 4B affinity chromatography. The proteins binding to Con A exhibited phosphomonoesterase (orthophosphoric monoester phosphohydrolase EC 3.1.3.2 ...
Childs, C. K., Hinson, Michael W., Johnson, Bob D., Sifford, Dewey H.   +3 more
core   +6 more sources

New Activity of a Protein from Canavalia ensiformis

Scientia Pharmaceutica, 2014
Concanavalin A is a legume lectin which preferentially agglutinates transformed cells and shows antitumor effects on human breast carcinoma cells in vitro and in vivo.
Vanya Petkova BOGOEVA, Lidiya Plamenova PETROVA, Anton Aleksandrov TRIFONOV   +2 more
doaj   +1 more source

MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in MiceSummary

Cellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Aberrant lymphocyte homing could potentially link inflammatory processes in the intestine and the liver, as distinct hepatobiliary diseases frequently develop as extra-intestinal manifestations in inflammatory bowel disease.
Angela Schippers, Jessica Hübel, Felix Heymann, Thomas Clahsen, Sreepradha Eswaran, Sarah Schlepütz, Robin Püllen, Nikolaus Gaßler, Klaus Tenbrock, Frank Tacke, Norbert Wagner   +10 more
doaj  

Comparison of Four Methods for the Determination of the Amylose Content in Foxtail Millet [PDF]

Shipin Kexue, 2023
In this study, the amylose contents in 24 commercial foxtail millet samples from major production provinces in China were determined by four different methods, namely, the improved national standard method (GB/T 15683-2008), the spectrophotometric method
LIU Jianlei, SHANG Bo, XING Xiaoting, ZHANG Dong, CHANG Liu, SUN Hui, DUAN Xiaoliang
doaj   +1 more source