Conformational Changes in Concanavalin A
Journal of Biological Chemistry, 1971 Abstract The circular dichroic spectrum of homogeneous concanavalin A shows changes in the near ultraviolet upon specific binding of α-methyl-d-mannoside. The far ultraviolet spectrum shows no evidence of α helical structure but most closely resembles the spectrum of the model for type II-β structure, poly-S-carboxymethyl-l-cysteine.
M N, Pflumm, J L, Wang, G M, Edelman
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Behenic Acid Monolayer and Bilayer Assemblies- A Study of Concanavalin A (Con A) Adsorption and its Interaction with Dextran Using Surface Plasmon Resonance Spectroscopy and Microscopy [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1993 Deposition of behenic acid (B.A) mono and bilayers onto gold coated surfaces was performed by Langmuir-Blodget dip-casting technique. Surface Plasmon resonance (SPR) and ellipsometry methods were employed for investigation of the monolayer and bilayer ...
Gholam Hossein Rounaghi +2 more
doaj
The enigma of RIPK1 in the liver: More than just a kinase
Molecular & Cellular Oncology, 2017 Receptor interacting protein kinase 1 (RIPK1) represents a key molecule in cell death. Here, we discuss our recent data on RIPK1 in liver injury and hepatocellular carcinoma development and put these into relation to previous experimental findings to ...
Mihael Vucur +3 more
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Concanavalin A Toxicity: Histological Studies
Experimental Biology and Medicine, 1976 SummaryCon A injected iv in doses of 200-600 μg produced vascular endothelial damage, hepatic necrosis, and lymphoid atrophy.
Nopanitaya, W, Hanker, J, Tyan, M
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A novel technique for selective NF-kappa B inhibition in Kupffer cells: contrary effects in fulminant hepatitis and ischaemia-reperfusion. [PDF]
, 2009 Background and aims: The transcription factor nuclear factor kappa B (NF-kB) has risen as a promising target for anti-inflammatory therapeutics. In the liver, however, NFkB inhibition mediates both damaging and protective effects.
A. Hartkorn +11 more
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Effects of arginine and ornithine supplementation to a high‐protein diet on selected cellular immune variables in adult cats [PDF]
, 2020 Background: Dietary protein and amino acid intake and composition can modulate immune function. Objectives: To evaluate the effects of high‐protein intake and arginine and ornithine supplementation on feline immune cells.
Kohn, Barbara +2 more
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Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods
Nanomaterials and Nanotechnology, 2014 Gold nanorod-based affinity sensors were developed utilizing concanavalin-A/dextran/glucose chemistry to detect glucose. The gold nanorods, synthesized using the seed-mediated method, were first coated with dextran sulfate.
Ching-An Peng, Sushil Pachpinde
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The neonatal splice variant of Nav1.5 potentiates in vitro invasive behaviour of MDA-MB-231 human breast cancer cells [PDF]
, 2007 Upregulation of functional voltage-gated Na+ channels (VGSCs) occurs in metastatic human breast cancer (BCa) in vitro and in vivo. The present study aimed to ascertain the specific involvement of the 'neonatal' splice variant of Nav1.5 (nNav1.5), thought
Brackenbury, William J. +3 more
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Order independent structural alignment of circularly permuted proteins
, 2004 Circular permutation connects the N and C termini of a protein and concurrently cleaves elsewhere in the chain, providing an important mechanism for generating novel protein fold and functions.
Binkowski, T. Andrew +2 more
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Advanced Science, EarlyView.Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source