Galactosyltransferase and Concanavalin A Agglutination of Cells [PDF]
A correlation has been observed between concanavalin A agglutination of various cell types and the presence of surface membrane galactosyltransferase (1- O -α-D-Galactosyl- myo -inositol:raffinose galactosyltransferase, EC 2.4.1.67) activity.
Kurt J. Isselbacher+3 more
openaire +3 more sources
Concanavalin A-induced autoimmune hepatitis is a well-established experimental model for immune-mediated liver injury. It has been widely used in the therapeutic studies of immune hepatitis. The in-depth analysis of dysregulated proteins from comparative
Qin Feng+13 more
doaj +1 more source
Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors
Pretreatment of normal human peripheral blood lymphocytes with the plant lectin, concanavalin A (Con A), results in inhibition of blast transformation and [3H]thymidine incorporation by untreated allogeneic lymphocytes from healthy volunteers donors in ...
L. Shou, S. Schwartz, R. Good
semanticscholar +1 more source
Biomacromolecular stereostructure mediates mode hybridization in chiral plasmonic nanostructures [PDF]
The refractive index sensitivity of plasmonic fields has been exploited for over 20 years in analytical technologies. While this sensitivity can be used to achieve attomole detection levels, they are in essence binary measurements that sense the presence/
Affar S. Karimullah+10 more
core +2 more sources
Interaction of the carbohydrate-binding protein concanavalin A with normal and transformed cells.
It has been shown that the carbohydrate-binding protein concanavalin A (ConA) can agglutinate leukemic cells and cells transformed by polyoma virus, simian virus 40, chemical carcinogens, and X-irradiation.
M. Inbar, L. Sachs
semanticscholar +1 more source
Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9 [PDF]
Objective: The cyclin-dependent kinase (CDK) inhibitor flavopiridol is currently being tested in clinical trials as anticancer drug. Beyond its cell death–inducing action, we hypothesized that flavopiridol affects inflammatory processes.
Berberich, Nina+11 more
core +1 more source
Subpopulations of liver coated vesicles resolved by preparative agarose gel electrophoresis. [PDF]
Rat liver clathrin coated vesicles (CVs) were separated into several distinct subpopulations using non-sieving concentrations of agarose, which allowed the separation of species differing primarily in surface charge.
Hill, DF+3 more
core
Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles [PDF]
Short interfering RNA (siRNA) attracts much attention for the treatment of various diseases. However, its delivery, especially via systemic routes, remains a challenge. Indeed, naked siRNAs are rapidly degraded, while complexed siRNAs massively aggregate
De Smedt, Stefaan+4 more
core +1 more source
Aim of investigation. To study at two models of immune hepatitis (Т-cellular and antibody origin) in mice damage of the liver, activity and destruction of its immunocompetent cells, thymus gland and the spleen, as well as the effect of curcumine ...
I. N. Alekseyeva+6 more
doaj
Hepatoprotective effect of syringic acid and vanillic acid on concanavalin a-induced liver injury.
The edible mushroom Lentinula edodes (shiitake) contains many bioactive compounds. In the present study, we cultivated L. edodes mycelia in solid medium and examined the hot-water extract (L.E.M.) for its suppressive effect on concanavalin A (ConA ...
Ayano Itoh+6 more
semanticscholar +1 more source