Results 101 to 110 of about 1,205,845 (301)

Business R&D expenditure and capital in Europe [PDF]

This study presents new estimates of business R&D capital stocks for 22 countries at the aggregate and industry levels. At 9 percent of GDP, the EU business R&D capital stock falls short of its US and Japanese counterparts.
Helmers, Christian, Schulte, Christian, Strauss, Hubert   +2 more
core  

Freezing-induced self-assembly of amphiphilic molecules [PDF]

, 2017
The self-assembly of amphiphilic molecules usually takes place in a liquid phase, near room temperature. Here, using small angle X-ray scattering (SAXS) experiments performed in real time, we show that freezing of aqueous solutions of copolymer ...
Albouy, P. A., Deville, S., Fulkar, A., Hakouk, K., Impéror-Clerc, M., Klotz, M., Liu, Q., Marcellini, M., Perez, J.   +8 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Demineralized bone matrix combined with concentrated growth factors promotes intervertebral fusion in a novel rat extreme lateral interbody fusion model

Journal of Orthopaedic Surgery and Research
Background Whether demineralized bone matrix (DBM) combined with concentrated growth factors (CGF) can accelerate intervertebral fusion remains uncertain.
Han Wu, Shaorong Li, WeiJian Wang, Jiaqi Li, Wei Zhang   +4 more
doaj   +1 more source

Comparing osteogenic effects between concentrated growth factors and the acellular dermal matrix

Brazilian Oral Research, 2018
Concentrated growth factor (CGF) is an autogenuous product that contains highly concentrated number of platelets and can be derived from venous blood by selective centrifugation.
Luo Huang, Rui Zou, Jinquan He, Kexiong Ouyang, Zhengguo Piao   +4 more
doaj   +1 more source

Hydrodynamic stability of swimming in ostraciid fishes: role of the carapace in the smooth trunkfish Lactophrys triqueter (Teleostei: Ostraciidae) [PDF]

, 2003
The hydrodynamic bases for the stability of locomotory motions in fishes are poorly understood, even for those fishes, such as the rigid-bodied smooth trunkfish Lactophrys triqueter, that exhibit unusually small amplitude recoil movements during ...
Bartol, Ian K., Gharib, Morteza, Gordon, Malcolm, Hove, Jay R., Webb, Paul W., Wiehs, Daniel   +5 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The determination of nutritional requirements for Safe Haven Food Supply System (emergency/survival foods) [PDF]

The Space Station Safe Haven Food System must sustain 8 crew members under emergency conditions for 45 days. Emergency Survival Foods are defined as a nutritionally balanced collection of high density food and beverages selected to provide for the ...
Ahmed, Selina
core   +1 more source

EFFICIENCY ANALYSIS OF COBB-DOUGLAS PRODUCTION FUNCTION IN KOJA CONTAINER TERMINAL, TANJUNG PRIOK PORT [PDF]

, 2015
Container terminal efficiency and productivity is important issues since productivity of container terminal in Indonesia is the low but the total handling charge is relatively high compared in ASEAN.
MAHARANI, Maharani, SUSILOWATI, Indah
core