Results 111 to 120 of about 1,205,845 (301)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Frontiers in Dental MedicineObjectivesA detailed meta-analysis and systematic search was conducted to assess the histologic and radiographic efficacy of autologous peripheral venous blood concentrates (APVBCs) for the socket preservation.DesignElectronic databases were searched ...
Yusheng Meng +4 more
doaj +1 more source
Dispersal and Concentration: Patterns of Latino Residential Settlement [PDF]
, 2004 Uses 1990 and 2000 Census data to determine how trends in residential settlement patterns among the Hispanic population changed over the course of a ...
Roberto Suro, Sonya Tafoya
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The knowledge economy and Dutch cities [PDF]
How can cities and metropolitan regions remain prosperous and competitive in a rapidly changing economy? In our paper we argue that ‘the knowledge economy’ offers perspectives for growth and added value creation.
Frank Van Oort, Otto Raspe
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
A comparative evaluation of concentrated growth factor and blood clot as scaffolds in regenerative endodontic procedures [PDF]
Kouqiang yixueObjective To evaluate and compare the treatment efficacy between concentrated growth factor(CGF) and blood clots(BC) as scaffolds in regenerative endodontic procedures(REPs).
XIE Nina, WEI Luming, YUAN Changyong, LIU Hao, LIU Yumiao, LIU Zongxiang, ZHU Shaoyue
doaj +1 more source
Slowly-growing gap-opening planets trigger weaker vortices
, 2016 The presence of a giant planet in a low-viscosity disc can create a gap edge in the disc's radial density profile sharp enough to excite the Rossby Wave Instability.
Hammer, Michael +2 more
core +1 more source
The Concentration of Epidermal Growth Factor in Japanese Mother's Milk.
Journal of Nutritional Science and Vitaminology, 1995 The concentration of epidermal growth factor (EGF) in human milk was measured by radioreceptor assay (RRA). Human milk samples collected from healthy Japanese mothers who delivered at full term were divided into 30 groups according to differences in the duration of lactation, seasons of the year and place of residence.
Y, Matsuoka, T, Idota
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source