Results 181 to 190 of about 15,736 (254)

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber   +8 more
wiley   +1 more source

From cognitive abstraction to adaptive behavior: neural bases of concept learning in autistic adolescents. [PDF]

open access: yesMol Autism
Chen Y   +11 more
europepmc   +1 more source

Functional screen for subtype specificity of voltage sensor–targeted Kv7 potentiators

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Voltage‐gated Kv7 (potassium channel subfamily Q [KCNQ]) potassium channels are powerful modulators of neuronal excitability. ICA‐069673 is a N‐aryl benzamide drug that targets the voltage‐sensing domain (VSD) of Kv7.2 with strong selectivity over Kv7.3 or Kv7.5, but the molecular basis of this selectivity remains poorly ...
Richard Kanyo   +6 more
wiley   +1 more source

Challenges and Coping Strategies of Migrant Parents in Türkiye: A Qualitative Study

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT This qualitative study explored the coping mechanisms used by 22 immigrant parents (nine men, 13 women) of Syrian, Iraqi, Afghan and Palestinian origin in Türkiye to cope with challenges related to food, shelter, healthcare and social exclusion while caring for their children.
Murat Altuntaş, Habibullah Akinci
wiley   +1 more source

Description of the rate-limiting hydrogen tunneling mechanism for plant 9- and 13-lipoxygenases. [PDF]

open access: yesProtein Sci
Kockler A   +7 more
europepmc   +1 more source

Impact of Transnational Family Separation on Parenting and Psychosocial Well‐Being for Black African Migrant Parents in Hamilton

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT In light of increased migration from sub‐Saharan Africa (SSA) to Hamilton in the past 5 years, this qualitative study explores the experiences of Black African migrant parents resettling in Hamilton, Canada. Using semi‐structured interviews and thematic analysis, four key themes emerged: (1) impact of migration and family separation stress on ...
Tsinat Semagn   +3 more
wiley   +1 more source

Narratives of Strength: Exploring Storytelling as a Tool for Resilience in Families

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Resilience, originally viewed as a psychological capacity to ‘bounce back’ from challenges, is now understood to be shaped by broader social inequalities, including gender, socio‐economic status, politics and ethnicity. This study explores how stories and narratives can help nurture resilience and improve well‐being among those residing in an ...
Chandra Ramamurthy   +3 more
wiley   +1 more source

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