Results 121 to 130 of about 4,278 (250)

Celebrating 10 years of #RSCPoster. [PDF]

Chem Sci
Cotterell N, de Jongh PAJM, Noël T, Junkers T, Reddy CM, Anastasaki A, Randviir E.   +6 more
europepmc   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Identification of Subtype-Selective Binding Sites in the Opioid Receptor Family. [PDF]

J Chem Inf Model
S Gomes AA, Guillot B, Jelsch C, Giraldo J.   +3 more
europepmc   +1 more source

An (αβ)2 Architecture of the Arabidopsis thaliana tRNA Splicing Endonuclease Complex: Structural Modeling and Evolutionary Analyses

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The tRNA splicing endonuclease (TSEN) removes introns from precursor tRNAs (pre‐tRNAs) in eukaryotes and archaea, but the architecture and subunit organization of plant TSEN remain poorly defined. Here, we integrated in planta bimolecular fluorescence complementation (BiFC) assays with AlphaFold3 (AF3)‐based structural modeling, molecular ...
Mohammad Moniruzzaman, Markus Englert, Kazuhito Akama   +2 more
wiley   +1 more source

Structural and Stability Analysis of de Novo Designed Proteins Incorporating a Plant Self‐Incompatibility Motif

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Artificial protein design enables the creation of stable scaffolds beyond those evolved in nature. Incorporation of native functional motifs into de novo scaffolds provides a promising strategy to mimic natural interactions while altering structural frameworks.
Hakuto Miyoshi, Koya Sakuma, Yoshitaka Moriwaki, Naoki Aoyama, Toma Kashima, Tohru Terada, Akimasa Miyanaga, Shinya Fushinobu   +7 more
wiley   +1 more source

The unscientific nature of the arguments of "Restorative Reproductive Medicine" and why we need to understand them. [PDF]

F S Rep
Paulson RJ.
europepmc   +1 more source

Tuning the Length of Filomicelles Prepared Via Templated Polymerization‐Induced Self‐Assembly

Small, EarlyView.
High‐aspect‐ratio polymeric micelles are attractive yet notoriously difficult to control in length. We reveal a counterintuitive and powerful solution: in supramolecularly templated PISA, adding non‐sticker polymer unexpectedly elongates the micelles, while post‐assembly sonication enables precise shortening with reduced dispersity.
Eleonora G. Hochreiner, Wiktoria Pioruńska, Gaëlle Mellot, Bence Fehér, Jean‐Michel Guigner, Viktoriia Drebezghova, Christophe Sinturel, Cornelus F. van Nostrum, Tina Vermonden, Jutta Rieger, Bas G. P. van Ravensteijn   +10 more
wiley   +1 more source

Structure-Based Development of Ultra-Broad-Spectrum 3C-Like Protease Inhibitors. [PDF]

Adv Sci (Weinh)
Su H, Nie T, Chen G, Xiong M, Zhang Y, Wu G, You M, Xie H, He J, Xiong Y, Hu H, Zhao W, Li M, Xiao G, Zhang L, Xu Y.   +15 more
europepmc   +1 more source

Quantitative Imaging of Human Hemoglobin Binding to Staphylococcus aureus With Single‐Molecule Resolution

Small, EarlyView.
Single‐molecule localization microscopy is exploited to quantify the number of hemoglobin copies bound to specific receptors on S. aureus wall. This quantification supports the design of a photoactive derivative of hemoglobin able to photo‐inactivate S.
Pietro Delcanale, Andrea Mussini, Òscar Gulías, Montserrat Agut, Melissa Berni, Stefano Pongolini, Stefano Bruno, Alessandro Casnati, Santi Nonell, Cristiano Viappiani, Stefania Abbruzzetti   +10 more
wiley   +1 more source

Rules railroad: Syntax-inspired diagrams for visualizing and understanding rule-based model specifications. [PDF]

PLoS Comput Biol
Patel RJ, Blinov ML.
europepmc   +1 more source