ABSTRACT Background The REACHE project started in January 2023, when a group of nursing and allied health professional academic researchers from the University of Liverpool, people with learning disabilities and representatives from local learning disability support organisations (People First Merseyside and MOWLL) collaborated to co‐produce a short ...
Helen Marshall +17 more
wiley +1 more source
Evaluating the Impact of Cartoon-Based Learning on Student Performance and Engagement in Medical Education: An Experimental Study. [PDF]
Kathiah R, Daya A P, Mp S, Selvakumar S.
europepmc +1 more source
A Bayes factor framework for unified parameter estimation and hypothesis testing
Abstract The Bayes factor, the data‐based updating factor of the prior to posterior odds of two hypotheses, is a natural measure of statistical evidence for one hypothesis over the other. We show how Bayes factors can also be used for parameter estimation.
Samuel Pawel
wiley +1 more source
Regionalization of the Developing Hypothalamus: The Prosomeric and Tripartite Models. [PDF]
Kapsimali M.
europepmc +1 more source
Lodge moraines: a common yet underreported end‐moraine type—a review
Lodge moraines are a distinct genetic type of end moraine formed by submarginal accretion of subglacial till; they are some of the largest end moraines in the world. Although underreported in the literature, they are of equal importance to push, dump and hummocky end moraines. End moraines are formed at glacier ice margins and show the extent of former
Mark D. Johnson +11 more
wiley +1 more source
The Chromaverse Is Colored by Triplexes Formed Through the Interactions of Noncoding RNAs with HNPRNPU, TP53, AGO, REL Proteins, Intrinsically-Disordered Regions, and Flipons. [PDF]
Herbert A.
europepmc +1 more source
Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley +1 more source
Perceptions of the 2D short animated videos for literacy against chronic diseases among adults with diabetes and/or hypertension: a qualitative study in primary care clinics. [PDF]
Pichayapinyo P +6 more
europepmc +1 more source
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville +6 more
wiley +1 more source
Mechanistic Basis of Cholesterol Binding and Transfer in NPC2: Insights From Molecular Dynamics Simulations. [PDF]
Patel S, Elghobashi-Meinhardt N.
europepmc +1 more source

