Results 91 to 100 of about 22,041,249 (385)
The application of multi-objective robust design methods in ship design [PDF]
, 1999 When designing large complex vessels, the evaluation of a particular design can be both complicated and time consuming. Designers often resort to the use of concept design models enabling both a reduction in complexity and time for evaluation.
Coates, Graham +2 more
core
Reliability Risk Evaluation during the Conceptual Design Phase
Acta Polytechnica, 2006 I (Relative Reliability Risk Index) is calculated and the idea of concept functionality graphs is presented. This method is applied on the example of seat suspensions for an off highway vehicle and the results are discussed.
G. Mamtani, G. Green
doaj
Towards a Comprehensive Hydrodynamic Model for the Feasibility Study of Motor Yachts
Journal of Marine Science and EngineeringThe design process for motor yachts primarily relies on the experience of designers, who draw upon their knowledge gained from working on similar hull forms.
Francesco Mauro +6 more
doaj +1 more source
Concept models for design practice
Bitácora Urbano Territorial, 2017 Concept models are common guides to living, and some more specialized ones, which have been developed and validated in other fields have been adopted by designers for use in their work. In particular, concept models serve as templates for decision-making
Stan Ruecker
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A concept design of supercritical CO2 cooled SMR operating at isolated microgrid region
, 2017 Most of the small modular reactor (SMR) concepts developed in the past have compact size and a longer life reactor core than the conventional nuclear power plants.
S. Kim +6 more
semanticscholar +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Design concept for nonarcing electrical connector [PDF]
, 1968 Connector plug automatically minimizes arcing during mating and demating. This plug uses a high-resistivity outer sheath as an extension to the regular pin contact.
Holmen, R. E.
core +1 more source