An approach to relate business and application services using ISDL [PDF]
, 2005 This paper presents a service-oriented design approach that allows one to relate services modelled at different levels of granularity during a design process, such as business and application services.
Dijkman, Remco +2 more
core +5 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The natural flow wing-design concept [PDF]
A wing-design study was conducted on a 65 degree swept leading-edge delta wing in which the wing geometry was modified to take advantage of the naturally occurring flow that forms over a slender wing in a supersonic flow field.
Bauer, Steven X. S., Wood, Richard M.
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Concept Blending and Dissimilarity: Factors for Creative Design Process: A Comparison between the Linguistic Interpretation Process and Design Process [PDF]
, 2009 This study investigated the design process in order to clarify the characteristics of the essence of the creative design process vis-à-vis the interpretation process, by carrying out design experiments.
Mukai, Futoshi +2 more
core
Active concept in pedestrian design
ARTEKS : Jurnal Teknik Arsitektur, 2017 Saat ini terdapat tren perancangan kota dengan konsep active living yang membuat penduduk kota menjadi lebih aktif bergerak, secara keseluruhan menjadikan kota lebih sehat (healthy city).
Christianto Hendrawan +1 more
doaj +1 more source
Water Supply and Drainage Design for Prefabricated Buildings Under the Green Building Concept
, 2023 Jingjing Sun
openalex +2 more sources
D-Graph: AI-Assisted Design Concept Exploration Graph [PDF]
, 2022 Shin Sano, Seiji Yamada
openalex +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Computer-aided design of large-scale integrated circuits - A concept [PDF]
, 1971 Circuit design and mask development sequence are improved by using general purpose computer with interactive graphics capability establishing efficient two way communications link between design engineer and system. Interactive graphics capability places
Schansman, T. T.
core +1 more source