Results 91 to 100 of about 1,412,249 (275)

Generalized differentiation with positively homogeneous maps: Applications in set-valued analysis and metric regularity [PDF]

open access: yes, 2009
We propose a new concept of generalized differentiation of set-valued maps that captures the first order information. This concept encompasses the standard notions of Frechet differentiability, strict differentiability, calmness and Lipschitz continuity ...
Pang, C. H. Jeffrey
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Balancing act: enhancing student comprehension of acid-base physiology through interactive, system-based teaching

open access: yesAdvances in Physiology Education
Acid-base physiology is widely recognized as one of the most conceptually challenging topics in undergraduate education due to its interdisciplinary nature and the necessity for both mechanistic and integrative understanding.
Tamara Dakic   +5 more
doaj   +1 more source

A reusable knowledge acquisition shell: KASH [PDF]

open access: yes
KASH (Knowledge Acquisition SHell) is proposed to assist a knowledge engineer by providing a set of utilities for constructing knowledge acquisition sessions based on interviewing techniques.
Keech, Virginia   +2 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Effect of Concept Mapping on Students\u27 Perceived Understanding of Science Concepts [PDF]

open access: yes, 2002
The effect of concept mapping on students\u27 perceived understanding of science concepts was investigated Concept maps as a tool to assess understanding, to identify misconceptions, and to correct misconceptions were also studied.
Warrick, Jennifer L.
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Concept mapping and conceptual change texts: a constructivist approach to address the misconceptions in nanoscale science and technology

open access: yesFrontiers in Education
Nanoscale Science and Technology (NST) is a rapidly evolving field with profound implications for various industries and our everyday lives. However, misconceptions among learners can hinder their ability to grasp the fundamental concepts of NST, thereby
Muhammad Naeem Sarwar   +10 more
doaj   +1 more source

Decision map for spatial decision making in urban planning [PDF]

open access: yes, 2005
In this paper, we introduce the concept of decision map and illustrate the way this new concept can be used effectively to support participation in spatial decision making and in urban planning. First, we start by introducing our spatial decision process
Chakhar, Salem   +3 more
core   +1 more source

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