Results 121 to 130 of about 270,662 (239)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

iDesignGPT enhances conceptual design via large language model agentic workflows. [PDF]

Nat Commun
Liu S, Shen Y, Zhang Y, Hou Z, Wang X, Luo J, Zhang Z.   +6 more
europepmc   +1 more source

A Conceptual Design of Smart Management System for Flooding Disaster. [PDF]

Int J Environ Res Public Health, 2021
Ibrahim T, Mishra A.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Radiation Hardened LIDAR Sensor: Conceptual Design, Testing, and Performance Evaluation. [PDF]

Sensors (Basel)
Jonasson ET, Kuhlmann C, Wood C, Skilton R.   +3 more
europepmc   +1 more source

Conceptual Design and Prototyping for a Primate Health History Knowledge Model. [PDF]

Adv Comput Vis Comput Biol (2020), 2021
Zhao MQ, Maldonado E, Kensler TB, Kohn LAP, Guatelli-Steinberg D, Wang Q.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Photocleavable Systems for Cell Biology: Conceptual Design across Molecular Modalities. [PDF]

Chembiochem
Yoshimura M, Inose T.
europepmc   +1 more source

CDFA method: a way to assess assembly and installation performance of aircraft system architectures at the conceptual design. [PDF]

Res Eng Des, 2022
Formentini G, Bouissiere F, Cuiller C, Dereux PE, Favi C.   +4 more
europepmc   +1 more source