Results 121 to 130 of about 329,719 (257)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Evaluation of product conceptual design based on Pythagorean fuzzy set under big data environment. [PDF]

Sci Rep, 2022
Ma LD, Wang WX, Xie JW, Zhang N, Hu NF, Wang ZA.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

An Evidence-Tiered Biomimetic Design Space Workflow for the Conceptual Design of Elderly-Care Robots. [PDF]

Biomimetics (Basel)
Zang W, Xiao C, Seong D.
europepmc   +1 more source

A semantic analysis-driven customer requirements mining method for product conceptual design. [PDF]

Sci Rep, 2022
Wu XY, Hong ZX, Feng YX, Li MD, Lou SH, Tan JR.   +5 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Biomimetic Wearable Device for Dysphagia: Digital Conceptual Design via KANO-EWM-TOPSIS and Extended FCBS Mapping. [PDF]

Biomimetics (Basel)
Yin K, Mao Z, Cui Y, Zhou A.
europepmc   +1 more source

A Conceptual Design of Smart Management System for Flooding Disaster. [PDF]

Int J Environ Res Public Health, 2021
Ibrahim T, Mishra A.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

iDesignGPT enhances conceptual design via large language model agentic workflows. [PDF]

Nat Commun
Liu S, Shen Y, Zhang Y, Hou Z, Wang X, Luo J, Zhang Z.   +6 more
europepmc   +1 more source