Results 131 to 140 of about 2,244,720 (326)
Proposal of a Conceptual Framework for Collaborative Design of Immersive Professional Training: Application to the Textile Industry [PDF]
, 2022 I. Bisson +6 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Implementation of Component-based Simulation Support Tool for Conceptual Design
Acta Polytechnica, 2004 Presented paper speaks about the problem of conceptual design stage simulation support. Simulation support is a very useful part of conceptual design system due to capability to verify ideas in early design stages.
T. Brandejský
doaj
GOMEA: A Conceptual Design of a Membrane Electrode Assembly for a Proton Exchange Membrane Electrolyzer. [PDF]
Membranes (Basel), 2023 Berning T, Bessarabov D.
europepmc +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Concept Design and Reliability
Acta Polytechnica, 2002 The paper outlines an approach to concept design that integrates the development of the design specification with multi-objective concept development. ‘Excursions’ are undertaken to explore particular aspects of the design, e.g., reliability, in order to
G. Cooper, G. Thompson
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Aspects Regarding the Innovative Conceptual Design for Children's Recreational Areas. [PDF]
Children (Basel), 2022 Bucur B, Ban A, Vlase S, Modrea A.
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Conceptual design study of the science payload for the Earth 2.0 mission
, 2022 Yonghe Chen +19 more
openalex +2 more sources