Results 51 to 60 of about 11,269 (252)

Semantic maps and mental representation

Linguistic Discovery, 2010
Semantic maps are usually assumed to describe a universal arrangement of different conceptual situations in a speaker's mind as determined by perceived relations of similarity between these conceptual situations. This paper provides a number of arguments
Sonia Cristofaro
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Mental search of concepts is supported by egocentric vector representations and restructured grid maps

Nature Communications, 2023
The human hippocampal-entorhinal system is known to represent both spatial locations and abstract concepts in memory in the form of allocentric cognitive maps.
Simone Viganò, Rena Bayramova, Christian F. Doeller, Roberto Bottini   +3 more
doaj   +1 more source

Development of research discourses: a conceptual map [PDF]

Journal of Advanced Nursing, 2016
AbstractAimThe aim of this study was to discuss: (1) how methodologies are constructed and perpetuated in the context of research paradigms; (2) what exactly constitutes a paradigm; (3) how the proposed conceptual map of discourse development provides a new and original method for understanding knowledge production.BackgroundIn nursing research ...
Freshwater, D, Cahill, J
openaire   +3 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Effect of Virtual Experiments Compared to Physical Experiments on Students’ Conceptual Understanding of Chemical Kinetics Concepts [PDF]

European Journal of STEM Education
Even though physical experiments are mandatory in science education, there has been an increasing demand for virtual experiments. This research aimed to investigate the impact of virtual experiments compared to physical experiments on students ...
Tadesse Hunegnaw, Tesfaye Demisse Hailegebreal, Dawit Asrat Getahun, Minaleshewa Atlabachew   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Mapas conceituais e questionários: uso ferramentas de avaliação do ensino em ações de extensão

Revista de Estudos e Pesquisas sobre Ensino Tecnológico, 2017
The integration of teaching, research and extension is an efficient didactic model in the agrarian sciences. Final students of the Technical Course on Fishery Resources followed the traditional process of fish meal production in the rural community Nossa
Rogério Ferreira Nakauth, Ana Carolina Souza Sampaio Nakauth, Sandra Regina Gregório   +2 more
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