Results 61 to 70 of about 11,269 (252)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Curbing domestic violence: instantiating C-K theory with formal concept analysis and emergent self organizing maps. [PDF]
In this paper we propose a human-centered process for knowledge discovery from unstructured text that makes use of Formal Concept Analysis and Emergent Self Organizing Maps.
Elzinga, Paul +3 more
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Cogent EducationThe study investigates the impact of digital conceptual mapping strategies on the learner’s mathematical academic performance in terms of mathematical concept formation and creative problem-solving skills based on the skill of flexibility.
Ahmed Elhilal
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Frammenti semantici. Riflessioni su descrizioni archivistiche e web semantico: Il caso dell’archivio Giovanni Testori [PDF]
, 2010 This doctoral thesis is about the possibility to put archival data (for example archival descriptions, authority records and so on) directly into semantic web, particularly using a technology called “Topic Maps”.
Vassallo, Salvatore
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Itinerarios de aprendizaje flexibles basados en mapas conceptuales
Journal of New Approaches in Educational Research, 2015 Se estudia el uso de itinerarios de aprendizaje basados en mapas conceptuales como una propuesta para un diseño instruccional más flexible que potencie el aprendizaje y se centre en el estudiante, generando procesos no lineales, caracterizando sus ...
Olga Lucía Agudelo +1 more
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Using Concept Maps to improve Scientific Communications
, 2008 Scientic talks, like scientic papers, are an important part of the scientic communication process. Good oral presentation skills, are vital to educational sciences, as well as to many other fields.
Alvares Marañón, Gonzalo +4 more
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Conceptual maps : representations of History teachers’ knowledge [PDF]
, 2007 Este texto pretende discutir o papel dos mapas de conceitos como representações gráficas do conhecimento do professor de história, aquando o desenho de um trajecto didáctico específico.
Melo, Maria do Céu +9 more
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