From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
ILO diagram: a novel conceptual model of intended learning outcomes [PDF]
, 2014 Achieving intended learning outcomes (ILOs) in education is an ongoing topic within distance learning and educational communities. The term "ILOs" has been introduced to indicate what learners will be able to do by the end of the course of study ...
Tangworakitthaworn, Preecha
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Designing a conceptual model for environmental indices influencing the attendancy in urban spaces with an arid and hot climate: A case study of Hakim Street in Isfahan [PDF]
کاوشهای جغرافیایی مناطق بیابانی, 2020 The climatic conditions in urban spaces with hot and arid regions always make it necessary to organize such spaces in urban planning and work out processes in proportion to the environmental conditions so that the quality of their attendancy can be ...
Kyoumars Habibi +3 more
doaj
Conceptual Modelling of Services.
J. Univers. Comput. Sci., 2012 Conceptual Modelling of ...
Ma, Hui +3 more
openaire +3 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
AI Communications 16 (2003) 279--289 279 IOS Press [PDF]
, 2004 This paper presents and motivates the use of a given knowledge representation designed to facilitate the knowledge sharing from heterogeneous sources for problem solving in environmental processes using an Agent based technology.
Conceptual Model To
core
Application of context knowledge in supporting conceptual design decision making [PDF]
, 2010 Conceptual design is the most important phase of the product life cycle as the decisions taken at conceptual design stage affect the downstream phases (manufacture, assembly, use, maintenance, and disposal) in terms of cost, quality and function ...
Xiu Tian Yan +4 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Drawing ability and its determinants: A conceptual model [PDF]
, 2019 There is a common agreement about the critical importance of drawing ability in design education. Discussions around the topic have mostly focused on two major arguments: 1) the effects of drawing ability on learning outcomes, as critical reflections on ...
Di Giovanni, M.
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source