Results 81 to 90 of about 552,487 (315)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
AI-assisted academic cheating: a conceptual model based on postgraduate student voices
Frontiers in Computer ScienceIntroductionAs AI tools become more widely used in higher education, concerns about AI-assisted academic cheating are growing. This study examines how postgraduate students interpret these behaviors.MethodsWe conducted an exploratory qualitative study ...
Nguyen Van Hanh, Nguyen Thi Duyen
doaj +1 more source
A conceptual model for manufacturing performance improvement
, 2009 Purpose: Important performance objectives manufacturers sought can be achieved through adopting the appropriate manufacturing practices. This paper presents a conceptual model proposing relationship between advanced quality practices, perceived ...
Karim, Azharul
core
A conceptual model for program-level assessment
Program-level assessment is a holistic approach for arranging assessments throughout a degree program that supports sequential development of discipline knowledge, transferable skills and career readiness.
Newsham-West, Richard +1 more
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Achieving Data Completeness in Electronic Medical Records: A Conceptual Model and Hypotheses Development [PDF]
, 2018 This paper aims at proposing a conceptual model of achieving data completeness in electronic medical records (EMR). For this to happen, firstly, we draw on the model of factors influencing data quality management to construct our conceptual model ...
Zowghi, Didar +11 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Modelling of Regional Economy Growth Strategy
Управленческие науки, 2017 Introduction, Purpose. Management of the regional economy development is experiencing rather serious methodological and instrumental difficulties. The diversified institutional constraints, private ownership of the companies do not allow constructively ...
I. S. Mezhov, E. V. Kletskova
doaj +1 more source
, 2016 Conceptual design has a decisive impact on the product development time, cost and success. This paper presents a new conceptual design method for achieving rapid and effective mapping from product design specification (PDS) to concept design. This method
Li, Rong +5 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source