Results 81 to 90 of about 2,253,125 (238)
Establishing a conceptual model for the sustainable wine district [PDF]
, 2011 This research will provide wide ranging, practical and sustainable benefits to regional wine marketers, policy makers, regional government tourism bodies and the allied wine groups to develop the quality branding and marketing of wine products in the ...
Cassidy, Frances +2 more
core +1 more source
Conceptual Modelling of Interaction
, 2011 The conceptual model of an information system cannot be considered to be complete after just specifying the structure and behaviour of the system. It is also necessary to specify how end users will interact with the system. Even though there are several proposals for modelling interaction, none of them have become widely known or widely used in ...
Aquino Salvioni, Nathalie Marylin +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Defining adaptation in a generic multi layer model : CAM: the GRAPPLE conceptual adaptation model [PDF]
, 2008 Authoring of Adaptive Hypermedia is a difficult and time consuming task. Reference models like LAOS and AHAM separate adaptation and content in different layers. Systems like AHA!
Bra, Paul M. E. de +4 more
core
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
Structured Review of Code Clone Literature [PDF]
, 2008 This report presents the results of a structured review of code clone literature. The aim of the review is to assemble a conceptual model of clone-related concepts which helps us to reason about clones. This conceptual model unifies clone concepts from a
Hordijk, Wiebe +2 more
core +2 more sources
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Towards a Theory of Conceptual Modelling [PDF]
, 2009 JUCS - Journal of Universal Computer Science Volume Nr.
openaire +2 more sources
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source