Results 101 to 110 of about 854,269 (252)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Editorial: Model-centered software and system development

open access: yesFrontiers in Computer Science, 2023
Heinrich C. Mayr, B. Thalheim
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

ADAPTATION OF SOFTWARE SYSTEMS TO USER TASKS BASED ON THE METHOD OF CONFIGURATION MODELING

open access: yesСовременные информационные технологии и IT-образование, 2018
In this paper, we discuss task of adaptation of software systems (PCs) and complexes (PCs) on the basis of the configuration modeling (MCM) method is considered.
Valentin V. Nechaev   +3 more
doaj   +1 more source

Functional Modeling in Conceptual Die Design [PDF]

open access: yes, 2003
The use of function has been recognized as an important part of the design process over last two decades, especially at the conceptual design stage, due to its critical role in determining the final product’s functionality.
Britton, G.A.   +2 more
core  

The role of modeling in troubleshooting: an example from electronics

open access: yes, 2015
Troubleshooting systems is integral to experimental physics in both research and instructional laboratory settings. The recently adopted AAPT Lab Guidelines identify troubleshooting as an important learning outcome of the undergraduate laboratory ...
Dounas-Frazer, Dimitri R.   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Modeling the Financial Behavior of Population (I) – Conceptual Assignations [PDF]

open access: yes
The paper shows a few conceptual assignations concerning the financial behavior of the population. Thus, there are defined attached predicates (the inclusion into the economic behavior category, the existence of a monetary factor, the action for goods ...
Dimitriu, Mihail   +3 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Considerations on the basis of medical reasoning for the use in AI applications

open access: yesFrontiers in Medicine
This study discusses the integration of artificial intelligence (AI) and machine learning (ML) in medical reasoning and decision-making, with a focus on the challenges and opportunities associated with the massive consumption of data required for ...
Adamantios Koumpis   +2 more
doaj   +1 more source

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