Results 71 to 80 of about 1,908,176 (323)
Developing Ontological Theories for Conceptual Models using Qualitative Research [PDF]
, 2005 Conceptual modelling is believed to be at the core of the IS discipline. There have been attempts to develop theoretical foundations for conceptual models, in particular ontological models as axiomatic reference systems.
Recker, Jan
core +1 more source
Tailoring temporal description logics for reasoning over temporal conceptual models [PDF]
, 2011 Temporal data models have been used to describe how data can evolve in the context of temporal databases. Both the Extended Entity-Relationship (EER) model and the Unified Modelling Language (UML) have been temporally extended to design temporal ...
A. Artale +23 more
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
VISUAL MODELS OF SYSTEMS ENGINEERING OF ADDITIVE MANUFACTURING PROCESSES
Надежность и качество сложных системBackground. The paper discusses methods for using visual systems engineering tools using the example of additive manufacturing processes. Materials and methods.
A.I. Vlasov, G.A. Volkov, K.V. Selivanov
doaj +1 more source
What is a Library Website, Anyway? Reconsidering Dominant Conceptual Models
Partnership: The Canadian Journal of Library and Information Practice and Research, 2021 In late 2019, Thompson Rivers University embarked on a multi-phase website usability project beginning with a website user survey, to be followed shortly afterward by usability testing and interviews.
Amy Paterson
doaj
, 2017 During his long writing and teaching career, Śākya Chokden (1428-1507) developed a novel, and in many respects unusual approach to the key systems of Buddhist thought and practice.
Komarovski, Yaroslav
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
BCAS: A Web-enabled and GIS-based Decision Support System for the Diagnosis and Treatment of Breast Cancer [PDF]
, 2001 For decades, geographical variations in cancer rates have been observed but the precise determinants of such geographic differences in breast cancer development are unclear. Various statistical models have been proposed.
Adya, Monica +3 more
core +1 more source
The Physics of Living Neural Networks
, 2007 Improvements in technique in conjunction with an evolution of the theoretical and conceptual approach to neuronal networks provide a new perspective on living neurons in culture.
Eckmann, Jean-Pierre +5 more
core +2 more sources
An approach to relate business and application services using ISDL [PDF]
, 2005 This paper presents a service-oriented design approach that allows one to relate services modelled at different levels of granularity during a design process, such as business and application services.
Dijkman, Remco +2 more
core +5 more sources