Results 71 to 80 of about 2,725,308 (288)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

THINK IN SASAK, SPEAK IN ENGLISH [PDF]

open access: yes, 2015
The emerging use of English in many fields have spread to all over the world. Contact between languages is then unavoidable. In Lombok, it can be witnessed three ways of how English has spread to the society, formal and informal learning, and non ...
Irawan, Lalu Ari   +2 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Depression and the medicalization of sadness: conceptualization and recommended help-seeking [PDF]

open access: yes, 2013
Critiques of the validity of the DSM diagnostic criteria for depressive disorder argue that it fails to differentiate between abnormal sadness due to internal dysfunction or depression (sadness without an identifiable cause), and normal sadness (sadness ...
Durà-Vilà, G, Leavey, G, Littlewood, R
core  

How career variety promotes the adaptability of managers: a theoretical model [PDF]

open access: yes, 2006
This paper presents a theoretical model showing how managerial adaptability develops from career variety over the span of the person’s career. By building on the literature of career theory, adult learning and development, and career adjustment, we oVer ...
Hall, Douglas T. Tim   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Individual and Structural Orientations in Socially Just Teaching: Conceptualization, Implementation, and Collaborative Effort [PDF]

open access: yes, 2010
This essay, drawn from theory, research, and the author’s practitioner research as a teacher educator, proposes a framework to inform teacher educators’ conceptualization and implementation of socially just teaching.
Chubbuck, Sharon
core   +1 more source

Situated conceptualization offers a theoretical account of social priming [PDF]

open access: yes
The theory of situated conceptualization is introduced, including its core assumptions about the construction and storage of situated conceptualizations, the production of pattern completion inferences in relevant situations, and the implementation ...
Barsalou, Lawrence W.
core   +1 more source

Tertiary time: The precariat's dilemma [PDF]

open access: yes, 2013
Progressive politics has always been about the struggle to reduce social inequities and inequalities. What takes priority depends on the type of society we live in.
Appadurai   +23 more
core   +1 more source

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