The infrapatellar fat pad from diseased joints inhibits chondrogenesis of mesenchymal stem cells [PDF]
Cartilage repair by bone marrow derived mesenchymal stem cells (MSCs) can be influenced by inflammation in the knee. Next to synovium, the infrapatellar fat pad (IPFP) has been described as a source for inflammatory factors. Here, we investigated whether
W Wei +6 more
doaj +1 more source
Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells [PDF]
Conditioned medium (CM) from clonal sub-populations of the pancreatic cancer cell line, MiaPaCa-2 with differing invasive abilities, were examined for their effect on in vitro invasion.
Alban +51 more
core +3 more sources
Physical conditions in the intergalactic medium [PDF]
Measurements of the spectrum of the cosmic microwave background radiation by COBE (Cosmic Background Explorer) limit the line integral of the electron pressure in intergalactic gas out to cosmological distances. The internal physical properties of diffuse bridges in the lobes of giant radio galaxies are also expected to reflect directly the pressure in
R. Subrahmanyan, L. Saripalli
openaire +1 more source
Estudy the Effect of Breast Cancer on Tlr2 Expression in Nb4 Cell [PDF]
Background: Breast cancer is the most common neoplasm in women and the most frequent cause of death in those between 35 and 55 years of age. All multicellular organisms have an innate immune system, whereas the adaptive or 'acquired' immune system is ...
Amirfakhri, S, Fern�ndez, N, Salimi, A
core +1 more source
Endothelial progenitor cells secrete a variety of growth factors that inhibit inflammation, promote angiogenesis and exert neuroprotective effects. Therefore, in this study, we investigated whether endothelial progenitor cell-conditioned medium might ...
Tao Wang, Xiao Fang, Zong-Sheng Yin
doaj +1 more source
Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics [PDF]
Antibiotic susceptibility of bacterial pathogens is typically evaluated using in vitro assays that do not consider the complex host microenvironment.
Coenye, Tom +10 more
core +6 more sources
Background Metastasis of breast cancer displays site-specificity towards bone. Recently, studies have emerged indicating that primary tumors may remotely influence creation of a pre-metastatic niche.
Karis Chin-Quee, Henry J. Donahue
doaj +1 more source
hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding. [PDF]
This work builds upon our findings that proteins secreted by hESCs exhibit pro-regenerative activity, and determines that hESC-conditioned medium robustly enhances the proliferation of both muscle and neural progenitor cells.
CONBOY, Irina M +7 more
core +2 more sources
Therapeutic applications of conditioned medium from adipose tissue [PDF]
AbstractFor the past number of decades, adipose tissue has attracted significant interest due to its complicated composition and versatile functions. Adipose tissue is no longer considered to be just an energy‐storing fat pad, but is also a key ring player in interaction networks between various organs and tissues.
Minjia Dai +3 more
openaire +2 more sources
Conditioned medium and secretome from epididymal epithelial cell cultures improve sperm kinetics and capacitation [PDF]
Background and Aim: Sperm maturation occurs in the epididymis through interactions with existing molecules inside the lumen. However, the mechanism of epididymis molecular transfer is currently unclear.
Luluk Yunaini, Dwi Ari Pujianto
doaj +1 more source

