Results 161 to 170 of about 790 (211)
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Psychopharmacology, 1998
Four experiments examined the effect of naloxone pretreatment on the expression and extinction of ethanol-induced conditioned place preference (experiments 1, 2, 4) or conditioned place aversion (experiments 1, 3). DBA/2 J mice received four pairings of a distinctive tactile (floor) stimulus (CS) with injection of ethanol (2 g/kg) given either ...
Cunningham Christopher L, C L Cunningham
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Four experiments examined the effect of naloxone pretreatment on the expression and extinction of ethanol-induced conditioned place preference (experiments 1, 2, 4) or conditioned place aversion (experiments 1, 3). DBA/2 J mice received four pairings of a distinctive tactile (floor) stimulus (CS) with injection of ethanol (2 g/kg) given either ...
Cunningham Christopher L, C L Cunningham
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PCP and conditioned place preferences
Pharmacology Biochemistry and Behavior, 1989Phencyclidine (PCP), in doses of 0.25, 0.35, and 0.45 mg/kg, was administered systemically to male Sprague-Dawley rats in order to determine if a positive conditioned place preference (CPP) could be achieved. Other subjects received systemic injections of morphine, 4.0 mg/kg, as a standard for comparison.
S H, Marglin +3 more
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Nicotine place preference in a biased conditioned place preference design
Pharmacology Biochemistry and Behavior, 2008Conditioned place preference (CPP) is often more effectively produced with nicotine using a biased procedure. Interpretation of results can be problematic, however, given that doses that produce CPP in rats have acute anxiolytic and residual anxiogenic effects. We tested three groups of male rats in a biased, 2-chambered apparatus.
Jennifer M, Brielmaier +2 more
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Place preference conditioning with methylphenidate and nomifensine
Brain Research, 1985The role of central catecholaminergic systems in place preference conditioning produced by methylphenidate and nomifensine was investigated. Several doses of either methylphenidate or nomifensine produced alterations in place preferences, while desipramine (10 mg/kg), a relatively selective noradrenergic uptake inhibitor, was ineffective, Haloperidol ...
M T, Martin-Iverson +2 more
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Conditioned place preferences for virtual alcohol cues
Behavioural Brain Research, 2023This study examined whether a conditioned place preference (CPP) could be established for a virtual reality (VR) room that previously contained virtual alcohol stimuli. 298 undergraduates with varying levels of alcohol use completed six, three-minute conditioning sessions in which they were confined to one of two visually-distinct VR rooms: one of the ...
Skyler M, Sklenarik +2 more
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Reinforcer revaluation and conditioned place preference
Physiology & Behavior, 1997Conditioned place preference (CPP) tests provide a novel way of testing an animal's ability to respond to direct manipulation of its motivational state. In the first of two studies, rats exhibited an appropriate preference for a place previously paired with either food or fluid, depending on their current motivational state (hungry or thirsty ...
S M, Perks, P G, Clifton
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What's conditioned in conditioned place preference?
Trends in Pharmacological Sciences, 2013Conditioned place preference (CPP) is a learned behavior shown in many vertebrates, including humans. CPP occurs when a subject comes to prefer one place more than others because the preferred location has been paired previously with rewarding events.
Joseph P, Huston +3 more
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Nicotine-induced conditioned place preference and conditioned place aversion in mice
Pharmacology Biochemistry and Behavior, 1995The motivational effects of nicotine were examined in mice using an unbiased place conditioning design. Swiss-Webster mice received four 15-min parings of a tactile stimulus with different doses of nicotine (0.25-2.0 mg/kg, IP). A different tactile stimulus was paired with saline injections.
F O, Risinger, R A, Oakes
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Journal of Psychopharmacology, 1992
Chronic exposure to very mild unpredictable stress has previously been found to reduce or abolish the acquisition of place preference conditioning. In the present study, chronic mild stress was found to abolish the acquisition of preferences for a distinctive environment paired with morphine (0.7 mg/kg).
M, Papp +3 more
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Chronic exposure to very mild unpredictable stress has previously been found to reduce or abolish the acquisition of place preference conditioning. In the present study, chronic mild stress was found to abolish the acquisition of preferences for a distinctive environment paired with morphine (0.7 mg/kg).
M, Papp +3 more
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Pharmacology Biochemistry and Behavior, 2000
In two experiments, we report that the place-conditioning paradigm can be used to demonstrate reinstatement of place preference/aversion by a drug prime following extinction training. In Experiment 1, rats were trained to prefer a chamber paired with morphine. Following extinction training, a morphine drug prime reinstated the morphine place preference.
L A, Parker, R V, Mcdonald
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In two experiments, we report that the place-conditioning paradigm can be used to demonstrate reinstatement of place preference/aversion by a drug prime following extinction training. In Experiment 1, rats were trained to prefer a chamber paired with morphine. Following extinction training, a morphine drug prime reinstated the morphine place preference.
L A, Parker, R V, Mcdonald
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