Results 171 to 180 of about 790 (211)

Preference and aversion for brain stimulations estimated by the conditioned place preference

Archives Internationales de Physiologie et de Biochimie, 1987
Rats implanted with chronic electrode into the medial forebrain bundle at the level of the hypothalamus (which elicited self-stimulation behaviour) display conditioned place preference after repeated stimulations of this area; conversely rats implanted into the mesencephalic dorso-medial tegmentum (which elicited switch-off behaviour) present ...
P, De Witte, M, Gewiss
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Opioidergic modulation of cocaine conditioned place preferences

Life Sciences, 1992
Recent studies have begun to assess the utility of opioid agonists and antagonists for the treatment of cocaine addiction. The present studies assess the effects of naltrexone or methadone on cocaine's reinforcing properties using the conditioned place preference (CPP) test.
E J, Bilsky, M J, Montegut, C L, Delong, L D, Reid   +3 more
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Methadone produces conditioned place preference in the rat

Pharmacology Biochemistry and Behavior, 1996
The appetitive properties of methadone were investigated using the conditioned place preference paradigm. Male Sprague-Dawley rats received conditioned place preference training for a 6-day period. The apparatus consisted of two chambers with distinctive visual and tactile cues, separated by removable doors.
R E, Steinpreis, A L, Rutell, F A, Parrett   +2 more
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Adenosine receptor agents and conditioned place preference

General Pharmacology: The Vascular System, 1997
1. The effects of different doses of the adenosine agonists N5-ethylcarboxamido-adenosine (NECA), R-isomer of N6-phenylisopropyladenosine (R-PIA), and N6-cyclohexyladenosine (CHA) or of the antagonists theophylline and 8-phenyltheophylline (8-PT) on conditioned place preference (CPP) have been studied. 2.
M R, Zarrindast, A A, Moghadamnia
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Clozapine attenuates cocaine conditioned place preference

Life Sciences, 1994
Clozapine, an atypical neuroleptic, has dopamine and serotonin antagonist actions that suggest its potential as a cocaine abuse pharmacotherapy. Yet, self-administration and discriminative stimulus studies in animals have reported both an enhancement and a partial blockade of cocaine's behavioral effects with clozapine.
T A, Kosten, E J, Nestler
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Clonidine produces a conditioned place preference in rats

Psychopharmacology, 1985
The possibility that the alpha-adrenergic agonist clonidine can act as a reinforcing agent was investigated using the conditioned place preference paradigm. Using two different variants of this method we were able to demonstrate reinforcing properties of clonidine at doses of 200 and 400 micrograms/kg.
K E, Asin, D, Wirtshafter
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Nicotine-induced conditioned place preferences in humans

Behavioural Brain Research
This study investigated whether a conditioned place preference (CPP) could be established for a virtual reality (VR) room paired with nicotine. Forty-four undergraduates with nicotine use completed a 3-day, within-subjects protocol. In session 1, participants were randomly assigned to receive either a 4 mg nicotine or placebo lozenge.
Skyler M. Sklenarik, Christopher N. Burrows, Robert S. Astur   +2 more
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Pipradrol conditioned place preference is blocked by SCH23390

Pharmacology Biochemistry and Behavior, 1992
We investigated the effect of the selective D1 dopamine antagonist, SCH23390, on the establishment of a pipradrol-conditioned place preference (CPP). Among various doses of pipradrol (6.25-75.0 mg/kg, SC), a CPP was established at 25.0 mg/kg. SCH23390 (0.16 mg/kg, IP) blocked the establishment of a CPP by this dose of pipradrol.
N M, White, N, Hiroi
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Dimenhydrinate produces a conditioned place preference in rats

Pharmacology Biochemistry and Behavior, 2003
Dimenhydrinate (DMH; trade names Gravol and Dramamine) is a compound of diphenhydramine (DP) and 8-chlorotheophylline in equimolar ratios. DMH has been reported to be abused by humans for its euphoric and hallucinogenic properties but few studies have evaluated its reinforcing effects in animals. To evaluate the hypothesis that DMH and its constituents
Alison G, Halpert, Mary C, Olmstead, Richard J, Beninger   +2 more
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Pentylenetetrazole can induce a conditioned place preference

Pharmacology Biochemistry and Behavior, 1991
Thirty-two male Sprague-Dawley rats were randomly selected into 4 groups (n = 8/group) and conditioned in a standard place preference task. The groups differed in the dose of pentylenetetrazole (PTZ) administered prior to conditioning trials. With respect to the three treatment groups, placement into the, initially, nonpreferred side of the CPP ...
D V, Gauvin, K N, Dormer, F A, Holloway
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