Results 171 to 180 of about 196,682 (209)

Nicotine-induced conditioned place preference in adolescent rats

Pharmacology Biochemistry and Behavior, 2011
A number of clinical reports have noted that women are more vulnerable to tobacco abuse than men, and adolescent females are especially vulnerable to nicotine addiction. Conditioned place preference (CPP) is a widely used technique for determining the rewarding effects of drugs with abuse potential in animal models.
Reka, Natarajan, John W, Wright, Joseph W, Harding   +2 more
openaire   +2 more sources

Dimenhydrinate produces a conditioned place preference in rats

Pharmacology Biochemistry and Behavior, 2003
Dimenhydrinate (DMH; trade names Gravol and Dramamine) is a compound of diphenhydramine (DP) and 8-chlorotheophylline in equimolar ratios. DMH has been reported to be abused by humans for its euphoric and hallucinogenic properties but few studies have evaluated its reinforcing effects in animals. To evaluate the hypothesis that DMH and its constituents
Alison G, Halpert, Mary C, Olmstead, Richard J, Beninger   +2 more
openaire   +2 more sources

Conditioned place preference produced by intra-hippocampal morphine

Pharmacology Biochemistry and Behavior, 1988
Unilateral microinjections of morphine sulphate into the rat hippocampus were found to produce a conditioned place preference, whereas equi-volume saline injections into the same region in a separate control group were without effect. The results are discussed in terms of possible reward or habituation functions of the hippocampus.
W A, Corrigall, M A, Linseman
openaire   +2 more sources

Domestic hen chicks’ conditioned place preferences for sound

Behavioural Processes, 2012
Food and sounds (white noise, a food call and the sound of other chicks) were used in an attempt to establish conditioned place preferences with domestic hen chicks. Thirty-two chicks were randomly allocated to one of the 4 groups, and exposed to a 3-compartment apparatus to establish a baseline of their movements across 4 15-min sessions.
Amy R, Jones, Lewis A, Bizo, T Mary, Foster   +2 more
openaire   +2 more sources

Cocaethylene produces conditioned place preference in rats

Pharmacology Biochemistry and Behavior, 1995
The ability of cocaethylene to produce either a conditioned place preference or a conditioned place aversion was tested in rats. Twelve male rats were administered 10 mg/kg cocaethylene and confined to their nonpreferred side of the conditioned place preference apparatus as determined on a baseline test day.
openaire   +2 more sources

Postretrieval propranolol disrupts a cocaine conditioned place preference

NeuroReport, 2006
The current study examined whether a postretrieval drug memory could be disrupted by the beta-adrenoceptor antagonist propranolol, administered following reactivation in a cocaine-mediated conditioned place preference paradigm. Following cocaine conditioning, rats were given a test of conditioned place preference, followed immediately by ...
Rick E, Bernardi, Kennon M, Lattal, Stephen P, Berger   +2 more
openaire   +2 more sources

Clonidine produces a conditioned place preference in rats

Psychopharmacology, 1985
The possibility that the alpha-adrenergic agonist clonidine can act as a reinforcing agent was investigated using the conditioned place preference paradigm. Using two different variants of this method we were able to demonstrate reinforcing properties of clonidine at doses of 200 and 400 micrograms/kg.
K E, Asin, D, Wirtshafter
openaire   +2 more sources

Dopaminergic substrates of amphetamine-induced place preference conditioning

Brain Research, 1982
The conditioned place preference paradigm was used to study the reinforcing properties of D-amphetamine. Rats were injected (i.p.) with D-amphetamine sulphate (0.5, 1.0 or 5.0 mg/kg) and 10 min later confined for 30 min to one side of a shuttle box in which each of the two compartments had distinctive features. On alternate (control) days they received
C, Spyraki, H C, Fibiger, A G, Phillips
openaire   +2 more sources

Dorsal/ventral hippocampus, fornix, and conditioned place preference

Hippocampus, 2001
AbstractConditioned place preference (CPP) is a learning paradigm requiring formation of associations between reward and particular locations. White and McDonald (Behav Brain Res 1993;55:269–281) demonstrated that amygdala (AMG) lesions impair, while fornix (Fx) lesions enhance learning of this task.
J, Ferbinteanu, R J, McDonald
openaire   +2 more sources

Pipradrol conditioned place preference is blocked by SCH23390

Pharmacology Biochemistry and Behavior, 1992
We investigated the effect of the selective D1 dopamine antagonist, SCH23390, on the establishment of a pipradrol-conditioned place preference (CPP). Among various doses of pipradrol (6.25-75.0 mg/kg, SC), a CPP was established at 25.0 mg/kg. SCH23390 (0.16 mg/kg, IP) blocked the establishment of a CPP by this dose of pipradrol.
N M, White, N, Hiroi
openaire   +2 more sources