Results 61 to 70 of about 247,657 (277)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Programmable responsive hydrogels inspired by classical conditioning algorithm
Nature Communications, 2019 Living systems inspired research on systems chemistry to mimic specific complex biological functions, but mimicking even the most elementary aspects of learning is a grand challenge. Here the authors demonstrate a programmable hydrogel-based model system,
Hang Zhang +3 more
doaj +1 more source
Lower and Upper Conditioning in Quantum Bayesian Theory [PDF]
, 2018 Updating a probability distribution in the light of new evidence is a very basic operation in Bayesian probability theory. It is also known as state revision or simply as conditioning.
Jacobs, Bart
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Associative memory stored by functional novel pathway rather than modifications of preexisting neuronal pathways [PDF]
, 2006 Associative conditioning involves changes in the processing pathways activated by sensory information to link the conditioned stimulus (CS) to the conditioned behavior.
Benjamin, Paul R +3 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Cerebellar-Dependent Learning in Larval Zebrafish [PDF]
, 2011 Understanding how neuronal network activity contributes to memory formation is challenged by the complexity of most brain circuits and the restricted ability to monitor the activity of neuronal populations in vivo.
Aizenberg, Mark, Schuman, Erin M.
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Enhanced fear limits behavioral flexibility in Shank2-deficient mice
Molecular Autism, 2022 Background A core symptom of autism spectrum disorder (ASD) is repetitive and restrictive patterns of behavior. Cognitive inflexibility has been proposed as a potential basis for these symptoms of ASD.
Miru Yun, Eunjoon Kim, Min Whan Jung
doaj +1 more source
The Mere Exposure Effect and Classical Conditioning [PDF]
, 2015 This study investigated Zajonc’s hypothesized link between the mere exposure effect and classical conditioning. In the first part of the experiment, participants were presented a photograph of a person.
Wong, Rosalyn
core +2 more sources