Results 1 to 10 of about 434,913 (295)

Thiotepa, Busulfan, Cyclophosphamide: Effective but Toxic Conditioning Regimen Prior to Autologous Hematopoietic Stem Cell Transplantation in Central Nervous System Lymphoma

Medical Sciences, 2023
In primary central nervous system lymphoma, two-year progression-free survival rates of up to 63 percent have been reported for first-line autologous stem cell transplantation after conditioning with the thiotepa busulfan cyclophosphamide regimen ...
Lebon Delphine, Debureaux Pierre-Edouard, Royer Bruno, Gruson Bérengère, Joris Magalie, Votte Patrick, Marolleau Jean-Pierre, Morel Pierre   +7 more
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CONDITIONING REGIMEN FOR LANGERHANS HISTIOCYTOSIS

Journal of Bone Marrow Transplantation and Cellular Therapy, 2021
Langerhans cell histiocytosis (LCH) is a rare disease, with an estimated incidence of 0.5 per 100,000 children in the United States of America1. HCL occurs due to differentiation of myeloid precursors into CD1a+ / CD207+ cells and is characterized by ...
Victor Gottardello Zecchin, MONICA DOS SANTOS CYPRIANO, GUSTAVO ZAMPERLINI   +2 more
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A Novel Modified Bu/Vp16/cy/Flu/Ara‐C Conditioning Regimen Enhances Outcomes for High‐Risk Acute Lymphoblastic Leukemia Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

Cancer Medicine
Purpose Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) effectively treats high‐risk acute lymphoblastic leukemia (ALL), yet challenges persist due to post‐transplant relapse and conditioning regimen toxicities.
Xiaoyan Zhao, Yifan Yao, Yan Sun, Ziwei Xu, Aiguo Liu, Xin Dong, Huafang Wang   +6 more
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The effect of cladribine-containing conditioning regimen on the efficacy and safety of allogeneic hematopoietic stem cell transplantation for children with acute lymphoblastic leukemia [PDF]

Stem Cell Research & Therapy
Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains a curative option for children with refractory, relapsed, or high-risk acute lymphoblastic leukemia (ALL).
Xinyu Li, Keyue Hu, Shaofen Lin, Liping Que, Yanfang Ye, Xiawei Han, Yin Wang, Xiaojun Wu, Liping Zhan, Dunhua Zhou, Yang Li, Danping Zhong, Jianpei Fang, Honggui Xu, Ke Huang   +14 more
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A novel conditioning regimen with pre-transplantation immunosuppression reduces the complication rates in hematopoietic stem cell transplantation in transfusion-dependent β-thalassemia [PDF]

Stem Cell Research & Therapy
Background Allo-HSCT is a curative therapy for patients with transfusion-dependent thalassemia (TDT). The high incidence of transplant-related complications is becoming an obstacle to safe and effective unrelated donor (URD) transplantation.
Huaqing Yang, Xinyu Li, Liping Que, Han Chen, Liping Zhan, Dunhua Zhou, Yang Li, Shaofen Lin, Yin Wang, Xiaojun Wu, Xiawei Han, Zhengzhou Wu, Danping Zhong, Ke Huang, Honggui Xu, Jianpei Fang   +15 more
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AntiCD30-Conjugated Antibody Plus Standard BEAM as Conditioning Regimen for Autologous Hematopoietic Stem Cell Transplantation in Systemic Anaplastic Large Cell Lymphoma [PDF]

Hematology Reports
Background/objectives: The outcome of refractory/relapsed systemic Anaplastic Large Cell Lymphoma (R/R-sALCL), especially for anaplastic lymphoma kinase-1 (ALK-1)-negative disease, remains dismal even after autologous hematopoietic stem cell ...
Panayotis Kaloyannidis, Basmah Al-Charfli, Biju George, Charbel Khalil, Nour Al-Moghrabi, Samar Mustafa, Dima Ibrahim, Mohammed Alfar, Firuz Ibrahim, Bassam Odeh, Mohammed Daryahya, Philip Shabo   +11 more
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Gynecological complications in long-term survivors after allogeneic hematopoietic cell transplantation—a single-center real-life cross-sectional study

Frontiers in Medicine, 2022
Background and objectivesHematopoietic stem cell transplantation (HCT) is a treatment for hematopoietic diseases. However, most cured female patients may suffer from premature ovarian insufficiency (POI) after HCT, which is mainly caused by the pre-HCT ...
Huina Su, Xinyu Zhou, Yanli Zhao, Yue Lu, DeYan Liu, Janping Zhang, Xin Yang   +6 more
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The association of conditioning regimen with cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation

Iranian Journal of Microbiology, 2020
Background and Objectives: Infections is yet one of the life-threatening complications of the hematopoietic stem cell transplantation (HSCT). The myeloablative and immunosuppressive conditioning regimens, which are administered before HSCT, dampen the ...
Masoud Mardani, Sara Abolghasemi, Shiva Shabani, Farzaneh Tavakoli, Anahita Saeedi, Sayeh Parkhideh, Abbas Hajifathali   +6 more
doaj   +1 more source

Case reports: Central nervous system involvement in patients with newly diagnosed multiple myeloma

Frontiers in Neurology, 2023
Multiple myeloma with central nervous system involvement (CNS-MM) is rare, having a poor outcome and occurring in newly diagnosed or relapsed/refractory patients. The current report concerns 3 cases of newly diagnosed MM patients who presented with skull-
Jinghua Liu, Jinghua Liu, Jing Shen, Daihong Liu   +3 more
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Reduced-dose carmustine (300 mg/m2) and melphalan as a conditioning regimen in multiple myeloma patients with CNS involvement: A case series

Current Problems in Cancer: Case Reports, 2023
Single-agent melphalan remains the gold standard for conditioning chemotherapy prior to autologous stem cell transplantation (ASCT) in the multiple myeloma (MM) setting. Melphalan's distribution in the central nervous system (CNS) is limited which raises
Garrett Rueda, Eric Smith, Nicolas De Padova, Hayley Heers, Ivan Komerdelj   +4 more
doaj   +1 more source