Results 21 to 30 of about 434,913 (295)

Expanding transplant options to patients over 50 years. Improved outcome after reduced intensity conditioning mismatched-unrelated donor transplantation for patients with acute myeloid leukemia: a report from the Acute Leukemia Working Party of the EBMT

open access: yesHaematologica, 2016
The outcome of patients undergoing HLA-matched unrelated donor allogeneic hematopoietic cell transplantation following reduced-intensity conditioning or myeloablative regimens is reported to be equivalent; however, it is not known if the intensity of the
Bipin N. Savani   +19 more
doaj   +1 more source

DAC-Based Conditioning Regimen Versus Standard Conditioning Regimen for Myelodysplastic Syndrome

open access: yesBlood, 2020
B ackground : Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only curable way for Myelodysplastic syndromes (MDS). There are still some patients have a poor prognosis after transplantation, including high frequency of relapse, poor response to salvage therapy and short overall survival. This study aimed to investigate whether DAC-
Yintian Zhang   +10 more
openaire   +1 more source

Thiotepa–busulfan–fludarabine (TBF) conditioning regimen in patients undergoing allogeneic hematopoietic cell transplantation for myelofibrosis: an outcome analysis from the Chronic Malignancies Working Party of the EBMT

open access: yes, 2021
Allogeneic hematopoietic cell transplantation (allo-HCT) remains the only curative option in MF. There is no consensus on the optimal conditioning regimen. We report outcomes of 187 patients with MF transplanted between 2010 and 2017 conditioned with TBF.
Chalandon, Yves   +79 more
core   +3 more sources

Peripheral blood stem cell graft compared to bone marrow after reduced intensity conditioning regimens for acute leukemia: a report from the ALWP of the EBMT

open access: yesHaematologica, 2016
Increasing numbers of patients are receiving reduced intensity conditioning regimen allogeneic hematopoietic stem cell transplantation. We hypothesized that the use of bone marrow graft might decrease the risk of graft-versus-host disease compared to ...
Bipin N. Savani   +20 more
doaj   +1 more source

Comparison of conditioning regimen toxicities among autologous stem cell transplantation eligible multiple myeloma patients: High-dose melphalan versus high-dose melphalan and bortezomib

open access: yes, 2018
Background Autologous hematopoietic stem cell transplantation (AHSCT) remains the standard of care for younger patients with multiple myeloma (MM). Currently, high-dose melphalan (HDM) is recommended as conditioning regimen before AHSCT. Preclinical data
Eda Aypar   +5 more
core   +3 more sources

Outcomes after alemtuzumab-containing reduced-intensity allogeneic transplantation regimen for relapsed and refractory non-Hodgkin lymphoma [PDF]

open access: yes, 2004
We report the outcomes after reduced-intensity conditioning allogeneic stem cell transplantation (RIT) for non-Hodgkin lymphoma (NHL) in 88 patients (low-grade NHL [LG-NHL], n = 41; high-grade NHL [HG-NHL], n = 37; mantle cell lymphoma [MCL], n = 10 ...
Mahendra, P   +37 more
core   +1 more source

Treosulfan-Based Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Pediatric Patients with Hemophagocytic Lymphohistiocytosis

open access: yesClinical Pediatric Hematology-Oncology, 2021
Hemophagocytic lymphohistiocytosis (HLH) is a fatal disease unless timely and effective treatment is given. Immunochemotherapy including etoposide, with or without hematopoietic stem cell transplantation (HCT), has improved the outcomes for patients with
Ho Joon Im, Sung Han Kang
doaj   +1 more source

Autologous hematopoietic stem cell transplantation in systemic sclerosis: nursing actions

open access: yesRevista Eletrônica de Enfermagem, 2014
The objective of this cross-sectional study was to identify the complications and the implemented nursing actions in systemic sclerosis patients undergoing autologous hematopoietic stem cell transplantation, during the conditioning regimen.
Carolina Scoqui Guimarães   +3 more
doaj   +1 more source

Dose intensity for conditioning in allogeneic hematopoietic cell transplantation: can we recommend “when and for whom” in 2021?

open access: yesHaematologica, 2021
Allogeneic hematopoietic stem-cell transplantation is a potentially curative therapy for various hematologic diseases. An essential component of this procedure is the pre-transplant conditioning regimen, which should facilitate engraftment and reduce or
Nico Gagelmann, Nicolaus Kröger
doaj   +1 more source

Optimizing Preparative Regimen for Umbilical Cord Blood Transplantation in Adult Acute Leukemia Patients: Acute Lymphoblastic Leukemia Requires Myeloablative Conditioning but Not Acute Myeloid Leukemia [PDF]

open access: yes, 2020
Cord blood transplantation (CBT) is a valuable alternative to bone marrow transplantation in adults without readily available donors. We conducted this study to investigate the feasibility of CBT for adult patients with acute leukemia with regards to ...
Han, JJ   +16 more
core   +3 more sources

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