Results 91 to 100 of about 689,894 (208)

Interference alignment at intermediate SNR with perfect or noisy CSI [PDF]

, 2010
Interference alignment is a new technique combining transmitter precoding and receiver interference suppression to achieve the optimal multiplexing gain in interference networks by exploiting knowledge of channel state information of all transmission ...
Miatton , Federico
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Synthesis and applications of silver nanowires

iScience
Summary: In the era of artificial intelligence, emerging fields such as smart windows, flexible sensors, human-computer interaction systems, and new energy technologies have exerted a profound influence on various aspects of our daily lives.
Jie Xu, Hongtao Gu
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Synergistic Design of Multicomponent Carbon Fillers and Structures for Emi Shielding Rubbers

Small Science
With the rapid development of highly integrated electronic devices, electromagnetic interference leakage through assembly gaps has become a critical challenge.
Weijian Zhang, Lechun Deng, Tengxun Yang, Fa Luo, Shifeng Wen, Yun Tang, Hongjing Wu, Qiang Chen   +7 more
doaj   +1 more source

Novel Fabrication Method for Pressure-Sensing Polymeric Optical Fiber (POF) Fabric with Non-Direct-Contact Conductive System

Applied Sciences
Considering the current limitations of intelligent interactive in electronic integration and luminescent modes, this paper proposes a novel fabrication method for pressure-sensing POF fabrics with a non-direct-contact conductive system.
Meng Li, Kun Hu, Lan Ge, Wenliang Xue, Aihua Dong, Qiu Tan   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Electromagnetic shielding effectiveness of weft-stretch conductive woven fabrics with integrated silver-plated elastic yarns

e-Polymers
Elastomeric conductive textiles are promising for wearable electromagnetic shielding, requiring maintained performance under stretch. Herein, weft-stretch conductive woven fabric integrating silver-plated elastic wrapped yarns were fabricated, achieving ...
Wang Linyu, Mao Lei, Hu Xiaofeng, Chen Jingjing, Zhao Caiyun   +4 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source