Results 81 to 90 of about 2,439,307 (250)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

An assessment of information seeking behavior of agricultural agents to retrieve need-based information in Sidama regional state of Ethiopia

Heliyon
The objective of the current study was to assess the levels of access of agricultural agents in the Sidama Region to agriculture-specific information from researchers and the media and its effect on their confidence in communicating with farmers.
Hailemesekel Zewedie Gebeyehu, Yohannes Shiferaw Jira   +1 more
doaj   +1 more source

An Efficient Construction of Confidence Regions via Swarm Intelligence and Its Application in Target Localization

IEEE Access, 2018
It is essential to enhance the speed and accuracy of the localization process to gain the robustness and instantaneous properties and to adapt from the practical environment of a confidence band.
Frank Po-Chen Lin, Frederick Kin Hing Phoa   +1 more
doaj   +1 more source

Analysis of Media Agenda-Setting Effects on Consumer Confidence in the Safety of the U.S. Food System [PDF]

Results from continuous tracking of consumer confidence and media coverage of food safety events over a 67 week period between May 2008 and August 2009 are reported.
Bharad, Abhishek Bhagwat, Degeneffe, Dennis J., Ferreira, Gustavo F.C., Harrison, R. Wes, Kinsey, Jean D.   +4 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Calibrating and Visualizing Some Bootstrap Confidence Regions

Axioms
When the bootstrap sample size is moderate, bootstrap confidence regions tend to have undercoverage. Improving the coverage is known as calibrating the confidence region. Consider testing H0:θ=θ0 versus H1:θ≠θ0.
Welagedara Arachchilage Dhanushka M. Welagedara, David J. Olive   +1 more
doaj   +1 more source

Noteworthy: Demographics, natural gas, electric power [PDF]

The regional economic outlook is quite positive. Broad-based hiring in every sector from energy to construction to services reflects the confidence employers have that the region is poised for sustained expansionDemography ; Energy ...
Pia M. Orrenius
core  

Observation of PeV Gamma Rays from the Monogem Ring with the Tibet Air Shower Array

, 2005
We searched for steady PeV gamma-ray emission from the Monogem ring region with the Tibet air shower array from 1997 February to 2004 October. No evidence for statistically significant gamma-ray signals was found in a region 111$\degr$ $\leq$ R.A. $
Amenomori, M, Ayabe, S, Chen, D, Cui, S W, Danzengluobu, Ding, L K, Ding, X H, Feng Cun Feng, Feng, Z Y, Gao, X Y, Geng, Q X, Guo, H W, He, H H, He, M, Hibino, K, Hotta, N, Hu, H, Hu, H B, Huang, J, Huang, Q, Jia, H Y, Kajino, F, Kasahara, K, Katayose, Y, Kato, C, Kawata, K, Labaciren, Le, G M, Li, J Y, Lu, S L, Lü, H, Meng, X R, Mizutani, K, Mu, J, Munakata, K, Nagai, A, Nanjo, H, Nishizawa, M, Ohnishi, M, Ohta, I, Onuma, H, Ouchi, T, Ozawa, S, Ren, J R, Saito, T Y, Saitô, T, Sakata, M, Sasaki, T, Shibata, M, Shiomi, A, Shirai, T, Sugimoto, H, Takita, M, Tan, Y H, Tateyama, N, Torii, S, Tsuchiya, H, Udo, S, Wang, H, Wang, X, Wang, Y G, Wu, H R, Xue Liang, Yamamoto, Y, Yan, C T, Yang, X C, Yasue, S, Ye, Z H, Yu, G C, Yuan, A F, Yuda, T, Zhang, H M, Zhang, J L, Zhang, N J, Zhang, X Y, Zhang, Y, Zhang, Yi, Zhaxi Sang Zhu, Zhou, X X   +78 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Role of magnetic resonance spectroscopy to differentiate high-grade gliomas from metastases

Tumor Biology, 2017
This study is to measure the diagnostic examination quality of magnetic resonance spectroscopy in differentiating high-grade gliomas from metastases.
Qun Wang, JiaShu Zhang, WeiLin Xu, XiaoLei Chen, JianMin Zhang, BaiNan Xu   +5 more
doaj   +1 more source