Results 81 to 90 of about 840,557 (391)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

OEDGE modeling of far-SOL tungsten impurity sources and screening in WEST

open access: yesNuclear Materials and Energy, 2022
The plasma background and impurity transport in the scrape-off layer (SOL) of the WEST tokamak are modeled for three discharges over a Psep power scan ranging between 1.5 and 2.35 MW. An extended modeling grid is used to investigate far-SOL sourcing from
J.B. Maeker   +10 more
doaj  

From scalar to string confinement

open access: yes, 2000
We outline a connection between scalar quark confinement, a phenomenologically successful concept heretofore lacking fundamental justification, and QCD. Although scalar confinement does not follow from QCD, there is an interesting and close relationship ...
A. B. Henriques   +37 more
core   +1 more source

Crystal growth in confinement

open access: yesNature Communications, 2022
AbstractThe growth of crystals confined in porous or cellular materials is ubiquitous in Nature and forms the basis of many industrial processes. Confinement affects the formation of biominerals in living organisms, of minerals in the Earth’s crust and of salt crystals damaging porous limestone monuments, and is also used to control the growth of ...
Felix Kohler   +2 more
openaire   +5 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Some views on monopoles and confinement [PDF]

open access: yes, 1995
Aspects of the monopole condensation picture of confinement are discussed. First, the nature of the monopole singularities in the abelian projection approach is analysed.
van der Sijs, A. J.
core   +2 more sources

Probing the ultimate plasmon confinement limits with a van der Waals heterostructure [PDF]

open access: yesScience, 2018
Light confined to a single atomic layer The development of nanophotonic technology is reliant on the ability to confine light to spatial dimensions much less than the wavelength of the light itself.
David Alcaraz Iranzo   +13 more
semanticscholar   +1 more source

CONFINEMENT AND LIBERATION [PDF]

open access: yes, 2005
This is a review of topics which haunted me for the last 40 years, starting with spontaneous symmetry breaking and ending with gauge/string/space-time correspondence. While the first part of this article is mostly historical, the second contains some comments, opinions and conjectures which are new. This work is prepared for the volume " Fifty Years of
openaire   +3 more sources

Confining Potentials [PDF]

open access: yesBrazilian Journal of Physics, 2019
16 pages, no ...
R. L. P. G. Amaral   +3 more
openaire   +2 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

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