Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Understanding the spectrum during the tearing mode locking by rotating RMP in J-TEXT
The rotating resonant magnetic perturbation (RMP) could lock the tearing mode (TM) and prevent disruption. It is found that the TM instantaneous frequency oscillates during TM locking on the RMP.
Da Li+18 more
doaj +1 more source
Active Matter in Lateral Parabolic Confinement: From Subdiffusion to Superdiffusion
In this work we studied the diffusive behavior of active brownian particles under lateral parabolic confinement. The results showed that we go from subdiffusion to ballistic motion as we vary the angular noise strength and confinement intensity.
Potiguar, F. Q., Ribeiro, H. E.
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
OEDGE modeling of far-SOL tungsten impurity sources and screening in WEST
The plasma background and impurity transport in the scrape-off layer (SOL) of the WEST tokamak are modeled for three discharges over a Psep power scan ranging between 1.5 and 2.35 MW. An extended modeling grid is used to investigate far-SOL sourcing from
J.B. Maeker+10 more
doaj
From scalar to string confinement
We outline a connection between scalar quark confinement, a phenomenologically successful concept heretofore lacking fundamental justification, and QCD. Although scalar confinement does not follow from QCD, there is an interesting and close relationship ...
A. B. Henriques+37 more
core +1 more source
16 pages, no ...
R. L. P. G. Amaral+3 more
openaire +2 more sources
Probing the ultimate plasmon confinement limits with a van der Waals heterostructure [PDF]
Light confined to a single atomic layer The development of nanophotonic technology is reliant on the ability to confine light to spatial dimensions much less than the wavelength of the light itself.
David Alcaraz Iranzo+13 more
semanticscholar +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
The effects of partial stable confinement on the voluntary activity of weanling thoroughbred foals : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Animal Science, Massey University, Palmerston North, New Zealand [PDF]
This thesis discusses an observational study, which evaluates the effects of partial stable confinement on the voluntary activity of weanling Thoroughbreds kept at pasture.
Lilly, Vanessa Maree
core