Results 91 to 100 of about 131,723 (308)

An experimental and numerical investigation on dynamic mechanical behavior and fracture characteristics of sandstone under active confining pressures

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
This study aims to investigate the dynamic mechanical properties and failure mechanisms of red sandstone under varying strain rates and confining pressures, using a modified confining pressure split Hopkinson pressure bar system, focus on investigating ...
Sheng-Qi Yang, Ye Li, Wen-Ling Tian, Bo-Wen Sun, Zhen Zhong, Xiao-Shuang Li   +5 more
doaj   +1 more source

Experimental investigation and constitutive model for lime mudstone [PDF]

, 2016
In order to investigate the mechanical properties of lime mudstone, conventional triaxial compression tests under different confining pressures (0, 5, 15 and 20 MPa) are performed on lime mudstone samples.
Baoyun Zhao, Jinxing Lai, Junbao Wang, Xinrong Liu, Zhanping Song   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A low-cost X-ray-transparent experimental cell for synchrotron-based X-ray microtomography studies under geological reservoir conditions [PDF]

, 2013
A new modular X-ray-transparent experimental cell enables tomographic investigations of fluid rock interaction under natural reservoir conditions (confining pressure up to 20 MPa, pore fluid pressure up to 15 MPa, temperature ranging from 296 to 473 K ...
Butler, Ian, Elphick, Stephen, Fusseis, Florian, Mäder, Urs, Steeb, Holger, Xiao, Xianghui, Zhu, Wenlu   +6 more
core   +1 more source

Superbrittleness of rocks at high confining pressure [PDF]

Proceedings of the International Conference on Deep and High Stress Mining, 2010
The paper discusses the variation of rock brittleness with confining pressure σ3 for rocks of different hardness, failed under triaxial compression with σ1 > σ2 = σ3. Experimental results presented in the paper show that hard rocks unlike relatively soft rocks increase their brittleness with rising confining pressure σ3. The harder the rock the greater
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Anisotropic Damage to Hard Brittle Shale with Stress and Hydration Coupling

Energies, 2018
Acoustic-wave velocities of shale rocks with different coring angles were tested by an acoustic-emission experiment under different confining pressures and soaking time of drilling fluid.
Junchuan Gui, Tianshou Ma, Ping Chen, Heyi Yuan, Zhaoxue Guo   +4 more
doaj   +1 more source

A study of CO2 flooding on wave velocities in the Naharkatiya oil reservoir of Upper Assam Basin [PDF]

, 2017
This paper studies the compressional-wave and shear-wave velocities in the laboratory in six conventional core plugs. These plugs were obtained from a depth of more than 3000 m from the producing horizons of Naharkatiya oil reservoir of Upper Assam Basin,
Kakoty, Miranda, Subrata Borgohain Gogoi
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source