Results 11 to 20 of about 529,930 (322)
Background: Previous studies showed that confocal laser endomicroscopy (CLE) images of brain tumors acquired by a first-generation (Gen1) CLE system using fluorescein sodium (FNa) contrast yielded a diagnostic accuracy similar to frozen surgical sections
Evgenii Belykh+13 more
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Background: Oral leukoplakia is a potentially malignant lesion with a clinical impression similar to different benign and malignant lesions. Ex vivo fluorescence confocal microscopy is a developing approach for a rapid “chairside” detection of oral ...
Veronika Shavlokhova+9 more
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Introduction to Confocal Microscopy [PDF]
Conventional microscopy requires viewing a thin-cut “section” of fixed or frozen tissue, and therefore cannot be used to view thick tissue samples or for in vivo investigations. In vivo microscopy requires a virtual, rather than a physical, section of the specimen.
Fernanda H. Sakamoto+5 more
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Ex Vivo Murine Skin Model for B. burgdorferi Biofilm
Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh ...
Jason P. Torres+5 more
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Background and purpose: While flecainide is now an accepted treatment for arrhythmias associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), its mechanism of action remains controversial.
Emma J. Steer+5 more
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New Endoscopic Imaging Technology Based on MEMS Sensors and Actuators
Over the last decade, optical fiber-based forms of microscopy and endoscopy have extended the realm of applicability for many imaging modalities. Optical fiber-based imaging modalities permit the use of remote illumination sources and enable flexible ...
Zhen Qiu, Wibool Piyawattanamatha
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Metalens-Based Miniaturized Optical Systems
Metasurfaces have been studied and widely applied to optical systems. A metasurface-based flat lens (metalens) holds promise in wave-front engineering for multiple applications.
Bo Li, Wibool Piyawattanametha, Zhen Qiu
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Advanced Fluorescence Microscopy Techniques—FRAP, FLIP, FLAP, FRET and FLIM
Fluorescence microscopy provides an efficient and unique approach to study fixed and living cells because of its versatility, specificity, and high sensitivity.
Gregor P. C. Drummen+2 more
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Raman imaging of protein in a model cheese system
Raman confocal microscopy is an increasingly useful technique when applied to food samples; it has the unique ability to interrogate the chemical structure, aligned with the same confocality capability that is available when using standard confocal ...
Elizabeth Nickless, Stephen E. Holroyd
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The voltage-gated potassium Kv1.3 channel is an essential component of vital cellular processes which is also involved in the pathogenesis of some autoimmune, neuroinflammatory and oncological diseases.
Nikita A. Orlov+6 more
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