Results 11 to 20 of about 529,930 (322)

Progress in Confocal Laser Endomicroscopy for Neurosurgery and Technical Nuances for Brain Tumor Imaging With Fluorescein

open access: yesFrontiers in Oncology, 2019
Background: Previous studies showed that confocal laser endomicroscopy (CLE) images of brain tumors acquired by a first-generation (Gen1) CLE system using fluorescein sodium (FNa) contrast yielded a diagnostic accuracy similar to frozen surgical sections
Evgenii Belykh   +13 more
doaj   +1 more source

Feasibility and Implementation of Ex Vivo Fluorescence Confocal Microscopy for Diagnosis of Oral Leukoplakia: Preliminary Study

open access: yesDiagnostics, 2021
Background: Oral leukoplakia is a potentially malignant lesion with a clinical impression similar to different benign and malignant lesions. Ex vivo fluorescence confocal microscopy is a developing approach for a rapid “chairside” detection of oral ...
Veronika Shavlokhova   +9 more
doaj   +1 more source

Introduction to Confocal Microscopy [PDF]

open access: yesJournal of Investigative Dermatology, 2012
Conventional microscopy requires viewing a thin-cut “section” of fixed or frozen tissue, and therefore cannot be used to view thick tissue samples or for in vivo investigations. In vivo microscopy requires a virtual, rather than a physical, section of the specimen.
Fernanda H. Sakamoto   +5 more
openaire   +3 more sources

Ex Vivo Murine Skin Model for B. burgdorferi Biofilm

open access: yesAntibiotics, 2020
Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh ...
Jason P. Torres   +5 more
doaj   +1 more source

Flecainide induces a sustained countercurrent dependent effect on RyR2 in permeabilized WT ventricular myocytes but not in intact cells

open access: yesFrontiers in Pharmacology, 2023
Background and purpose: While flecainide is now an accepted treatment for arrhythmias associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), its mechanism of action remains controversial.
Emma J. Steer   +5 more
doaj   +1 more source

New Endoscopic Imaging Technology Based on MEMS Sensors and Actuators

open access: yesMicromachines, 2017
Over the last decade, optical fiber-based forms of microscopy and endoscopy have extended the realm of applicability for many imaging modalities. Optical fiber-based imaging modalities permit the use of remote illumination sources and enable flexible ...
Zhen Qiu, Wibool Piyawattanamatha
doaj   +1 more source

Metalens-Based Miniaturized Optical Systems

open access: yesMicromachines, 2019
Metasurfaces have been studied and widely applied to optical systems. A metasurface-based flat lens (metalens) holds promise in wave-front engineering for multiple applications.
Bo Li, Wibool Piyawattanametha, Zhen Qiu
doaj   +1 more source

Advanced Fluorescence Microscopy Techniques—FRAP, FLIP, FLAP, FRET and FLIM

open access: yesMolecules, 2012
Fluorescence microscopy provides an efficient and unique approach to study fixed and living cells because of its versatility, specificity, and high sensitivity.
Gregor P. C. Drummen   +2 more
doaj   +1 more source

Raman imaging of protein in a model cheese system

open access: yesJournal of Spectral Imaging, 2020
Raman confocal microscopy is an increasingly useful technique when applied to food samples; it has the unique ability to interrogate the chemical structure, aligned with the same confocality capability that is available when using standard confocal ...
Elizabeth Nickless, Stephen E. Holroyd
doaj   +1 more source

Combining mKate2-Kv1.3 Channel and Atto488-Hongotoxin for the Studies of Peptide Pore Blockers on Living Eukaryotic Cells

open access: yesToxins, 2022
The voltage-gated potassium Kv1.3 channel is an essential component of vital cellular processes which is also involved in the pathogenesis of some autoimmune, neuroinflammatory and oncological diseases.
Nikita A. Orlov   +6 more
doaj   +1 more source

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