Results 41 to 50 of about 744,123 (317)

Observation of Real Contact Area Using Laser Microscope with Wide Field of View

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2011
In tribology, a contact condition between mating surfaces is very important to reduce friction and raise their lifetime. Direct observation of apparent contact area is necessary for a better understanding of the contact condition.
Isami NITTA, Rintaro EBUCHI, Yukiko YASUDA, Hirotoshi TERAO   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Acquisition and annotation in high resolution in vivo digital biopsy by confocal microscopy for diagnosis in oral precancer and cancer

Frontiers in Oncology, 2023
IntroductionScanned fibre endomicroscopes are full point-scanning confocal microscopes with submicron lateral resolution with an optical slice thickness thin enough to isolate individual cell layers, allow active positioning of the optical slice in the z-
Tami Yap, Tami Yap, Ivy Tan, Ivy Tan, Rishi S. Ramani, Nirav Bhatia, Paula Demetrio de Souza Franca, Paula Demetrio de Souza Franca, Chris Angel, Caroline Moore, Thomas Reiner, Lindsay Bussau, Michael J. McCullough, Michael J. McCullough   +13 more
doaj   +1 more source

Confocal measurement of microplastics uptake by plants

MethodsX, 2019
Graphical ...
Lianzhen Li, Yongming Luo, W. Peijnenburg, Ruijie Li, Jie Yang, Qian Zhou   +5 more
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Virtual Histology Staining of Skin Tissue using Ex Vivo Confocal Microscopy and Deep Learning [PDF]

Journal of Biomedical Physics and Engineering
Background: The use of Hematoxylin-and-Eosin (H&E) staining is widely accepted as the most reliable method for diagnosing pathological tissues. However, the conventional H&E staining process for tissue sections is time-consuming and requires significant ...
Mahmoud Bagheri, Alireza Ghanadan, Mobin Saboohi, Maryam Daneshpazhooh, Fatemeh Atyabi, Marjaneh Hejazi   +5 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Ex Vivo Murine Skin Model for B. burgdorferi Biofilm

Antibiotics, 2020
Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh ...
Jason P. Torres, Alireza G. Senejani, Gauri Gaur, Michael Oldakowski, Krithika Murali, Eva Sapi   +5 more
doaj   +1 more source

Spatial Correlations and Distribution of Competence Gene Expression in Biofilms of Streptococcus mutans

Frontiers in Microbiology, 2021
Streptococcus mutans is an important pathogen in the human oral biofilm. It expresses virulent behaviors that are linked to its genetic competence regulon, which is controlled by comX. Expression of comX is modulated by two diffusible signaling peptides,
Ivan P. Ishkov, Justin R. Kaspar, Stephen J. Hagen   +2 more
doaj   +1 more source

Confocal imaging-guided laser ablation of basal cell carcinomas: an ex vivo study

Journal of Investigative Dermatology, 2014
Laser ablation is a promising approach for minimally invasive removal of superficial and early nodular basal cell carcinomas (BCCs) (Smucler et al. , 2008, 2012).
Heidy Sierra, M. Cordova, C. Chen, M. Rajadhyaksha   +3 more
semanticscholar   +1 more source