Results 31 to 40 of about 739,261 (262)
A mode generator and multiplexer at visible wavelength based on all-fiber mode selective coupler
Nanophotonics, 2020 Using an all-fiber mode selective coupler (MSC) at the visible band, here we experimentally demonstrate a generating and wavelength multiplexing scheme for the cylindrical vector (CV) and vortex beams (VBs).
Yao Han +8 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Frontiers in Oncology, 2023 IntroductionScanned fibre endomicroscopes are full point-scanning confocal microscopes with submicron lateral resolution with an optical slice thickness thin enough to isolate individual cell layers, allow active positioning of the optical slice in the z-
Tami Yap +13 more
doaj +1 more source
The development of a time-resolved confocal microscope for single molecule detection of luminescent polymers [PDF]
, 2007 This report details the construction and testing of a confocal microscope for use in single molecule fluorescence spectroscopy. With the prospect of making time-resolved lifetime and spectral measurements of π-conjugated polymers in the condensed phase ...
Mc Auley, Frances
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Virtual Histology Staining of Skin Tissue using Ex Vivo Confocal Microscopy and Deep Learning [PDF]
Journal of Biomedical Physics and EngineeringBackground: The use of Hematoxylin-and-Eosin (H&E) staining is widely accepted as the most reliable method for diagnosing pathological tissues. However, the conventional H&E staining process for tissue sections is time-consuming and requires significant ...
Mahmoud Bagheri +5 more
doaj +1 more source
Three-dimensional imaging confocal profiler without in-plane scanning
, 2020 Most 3D metrological microscopes used today require a scanning through the optical axis, which is time consuming. The common techniques are Coherence Scanning Interferometry (CSI), Imaging Confocal Microscopy (ICM), and Focus Variation (FV).
Bermúdez, Carlos +4 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Ex Vivo Murine Skin Model for B. burgdorferi Biofilm
Antibiotics, 2020 Borrelia burgdorferi, the causative agent of Lyme disease, has been recently shown to form biofilm structures in vitro and in vivo. Biofilms are tightly clustered microbes characterized as resistant aggregations that allow bacteria to withstand harsh ...
Jason P. Torres +5 more
doaj +1 more source
Frontiers in Microbiology, 2021 Streptococcus mutans is an important pathogen in the human oral biofilm. It expresses virulent behaviors that are linked to its genetic competence regulon, which is controlled by comX. Expression of comX is modulated by two diffusible signaling peptides,
Ivan P. Ishkov +2 more
doaj +1 more source