Results 11 to 20 of about 3,678,372 (337)
Conformational Dynamics of Insulin [PDF]
Frontiers in Endocrinology, 2011 We have exploited a prandial insulin analogue (insulin lispro, the active component of Humalog®; Eli Lilly and Co.) to elucidate the underlying structure and dynamics of insulin as a monomer in solution.
Qing-xin eHua +2 more
doaj +3 more sources
Conformational dynamics and enzyme evolution [PDF]
Journal of The Royal Society Interface, 2018 Enzymes are dynamic entities, and their dynamic properties are clearly linked to their biological function. It follows that dynamics ought to play an essential role in enzyme evolution. Indeed, a link between conformational diversity and the emergence of
D. Petrović +3 more
semanticscholar +4 more sources
Opinion Dynamics Under Conformity [PDF]
SSRN Electronic Journal, 2012 We present a model of opinion formation where individuals repeatedly engage in discussion and update their opinion in a social network similarly to the DeGroot model. Abstracting from the standard assumption that individuals always report their opinion truthfully, agents in our model interact strategically in the discussion such that their stated ...
Buechel, Berno +2 more
openaire +3 more sources
Nature Communications, 2021 The emergence of SARS-CoV-2 Kappa and Beta variants with enhanced transmissibility and resistance to neutralizing antibodies has created new challenges for the control of the ongoing COVID-19 pandemic.
Yifan Wang +10 more
semanticscholar +1 more source
Conformal fluid dynamics [PDF]
Nuclear Physics B, 2006 We present a conformal theory of a dissipationless relativistic fluid in 2 space-time dimensions. The theory carries with it a representation of the algebra of 2-$D$ area-preserving diffeomorphisms in the target space of the complex scalar potentials. A complete canonical description is given, and the central charge of the current algebra is calculated.
Jarvis, P. D., van Holten, J. W.
openaire +3 more sources
bioRxiv, 2022 The Amino Acid-Polyamine-Organocation transporter GadC contributes to the survival of pathogenic bacteria under extreme acid stress by exchanging extracellular glutamate for intracellular GABA.
D. D. Alamo +5 more
semanticscholar +1 more source
Porosity in Conformal Dynamical Systems [PDF]
Mathematical Proceedings of the Cambridge Philosophical Society, 2021 AbstractIn this paper we study various aspects of porosities for conformal fractals. We first explore porosity in the general context of infinite graph directed Markov systems (GDMS), and we show that their limit sets are porous in large (in the sense of category and dimension) subsets.
Chousionis, Vasileios +1 more
openaire +2 more sources
Structure and conformational dynamics of Clostridioides difficile toxin A
Life Science Alliance, 2022 This study presents a complete structural model of TcdA holotoxin and sheds new lights into the conformational dynamics of TcdA and its roles in TcdA intoxication.
Baohua Chen +10 more
semanticscholar +1 more source
Nature Communications, 2021 To understand how RNA dynamics is regulated and connected to its function, we investigate the folding, conformational dynamics and robustness of Xrn1 resistance of a set of flaviviral xrRNAs using SAXS, smFRET and in vitro enzymatic assays.
Xiaolin Niu +6 more
semanticscholar +1 more source
SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility
bioRxiv, 2021 The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has killed over 5 million people and is causing a devastating social and economic impact all over the world.
M. Valério +4 more
semanticscholar +1 more source