Results 71 to 80 of about 1,031,416 (263)

A typology of four notions of confounding in epidemiology

, 2017
Confounding is a major concern in epidemiology. Despite its significance, the different notions of confounding have not been fully appreciated in the literature, leading to confusion of causal concepts in epidemiology.
Etsuji Suzuki
core   +2 more sources

Methodological biases in observational hospital studies of COVID-19 treatment effectiveness: pitfalls and potential

Frontiers in Medicine
IntroductionThis study aims to discuss and assess the impact of three prevalent methodological biases: competing risks, immortal-time bias, and confounding bias in real-world observational studies evaluating treatment effectiveness.
Oksana Martinuka, Derek Hazard, Hamid Reza Marateb, Hamid Reza Marateb, Marjan Mansourian, Marjan Mansourian, Miguel Ángel Mañanas, Miguel Ángel Mañanas, Sergio Romero, Sergio Romero, Manuel Rubio-Rivas, Martin Wolkewitz   +11 more
doaj   +1 more source

Confounding and control [PDF]

This paper deals both with the issues of confounding and of control, as the definition of a confounding factor is far from universal and there exist different methodological approaches, ex ante and ex post, for controlling for a confounding factor.
Guillaume Wunsch
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Why We Should Teach Causal Inference: Examples in Linear Regression With Simulated Data

Journal of Statistics Education, 2020
Basic knowledge of ideas of causal inference can help students to think beyond data, that is, to think more clearly about the data generating process.
Karsten Lübke, Matthias Gehrke, Jörg Horst, Gero Szepannek   +3 more
doaj   +1 more source

Removal of ineligible outcome cases reduces confounding

, 2018
Alexander M Walker,1 Sebastian Schneeweiss,2 Maral DerSarkissian,3 Mei Sheng Duh4 1World Health Information Science Consultants, Newton, MA, USA; 2Division of Pharmacoepidemiology, Department of Medicine, Brigham & Women’s Hospital and Harvard ...
Schneeweiss S, Duh MS, Walker AM, DerSarkissian M   +3 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Use of E-values for addressing confounding in observational studies-an empirical assessment of the literature. [PDF]

, 2020
BACKGROUND E-values are a recently introduced approach to evaluate confounding in observational studies. We aimed to empirically assess the current use of E-values in published literature.
Ioannidis, John P A, Tan, Yuan Jin, Blum, Manuel, Blum, Manuel R   +3 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Spatiotemporal models with confounding effects: application on under-five mortality across four sub-Saharan African countries

Frontiers in Public Health
BackgroundDifferent strategies have been developed to minimize under-five mortality (U5M) in sub-Saharan African (sSA) countries; however, it is still a major health concern for children in the region.
Haile Mekonnen Fenta, Haile Mekonnen Fenta, Ding-Geng Chen, Ding-Geng Chen, Temesgen T. Zewotir, Najmeh Nakhaei Rad   +5 more
doaj   +1 more source