Results 61 to 70 of about 1,031,416 (263)

SpaCE: The Spatial Confounding Environment

open access: yes, 2023
SpaCE: The Spatial Confounding Environment is a benchmarking dataset for causal inference incorporating spatial structure. In particular, SpaCE datasets contain real confounder and exposure/treatment data inspired by environmental health studies.
Audirac, Michelle   +3 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

The Entry of Randomized Assignment into the Social Sciences

open access: yesJournal of Causal Inference, 2019
Although the concept of randomized assignment in order to control for extraneous confounding factors reaches back hundreds of years, the first empirical use appears to have been in an 1835 trial of homeopathic medicine.
Jamison Julian C.
doaj   +1 more source

Information Theoretic Causal Effect Quantification

open access: yesEntropy, 2019
Modelling causal relationships has become popular across various disciplines. Most common frameworks for causality are the Pearlian causal directed acyclic graphs (DAGs) and the Neyman-Rubin potential outcome framework.
Aleksander Wieczorek, Volker Roth
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Demographic Shortcuts Account for Most of the Apparent Accuracy of Four-Class Gait-Based Differential Diagnosis in Neurodegenerative Disease: An Interpretability-Driven Audit of Machine Learning on a Public Gait Benchmark

open access: yesBioengineering
Machine-learning gait studies often report high accuracy for separating neurodegenerative diseases, but rarely test whether this reflects pathology or the demographic differences that accompany disease in convenience cohorts.
Zheng Wang, Yitong Xia, Guifeng Zhang
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Concurrent confounding conditions in adherence study population.

open access: yes, 2023
Concurrent confounding conditions in adherence study population.
Charuhas V. Thakar (6236306)   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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