Results 41 to 50 of about 1,001,591 (299)

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo   +9 more
wiley   +1 more source

A note on a sensitivity analysis for unmeasured confounding, and the related E-value

open access: yesJournal of Causal Inference, 2020
Unmeasured confounding is one of the most important threats to the validity of observational studies. In this paper we scrutinize a recently proposed sensitivity analysis for unmeasured confounding.
Sjölander Arvid
doaj   +1 more source

The principles of orthogonality and confounding in replicated experiments - With Seven Text-figures

open access: yes, 1933
The principle of orthogonality in replicated experiments is discussed and the dangers of non-orthogonality emphasised. The modifications necessary in the ordinary procedure of the analysis of variance when applied to non-orthogonal data are developed ...
Yates, F.
core   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine   +17 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben   +4 more
wiley   +1 more source

On the definition of a confounder

open access: yesThe Annals of Statistics, 2013
Published in at http://dx.doi.org/10.1214/12-AOS1058 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
VanderWeele, Tyler J., Shpitser, Ilya
openaire   +9 more sources

Accurate modeling of confounding variation in eQTL studies leads to a great increase in power to detect trans-regulatory effects [PDF]

open access: yes, 2011
Expression quantitative trait loci (eQTL) studies are an integral tool to investigate the genetic component of gene expression variation. A major challenge in the analysis of such studies are hidden confounding factors, such as unobserved covariates or ...
Neil Lawrence   +2 more
core  

Confounding

open access: yes, 2017
This chapter gives the definition of confounding, a central issue in epidemiology and its dependence on two associations, with exposure and with outcome. It explains confounding in trials, cohort and case-control studies, and Simpson’s paradox.
Mark Elwood
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

Ensemble Variability as a Signal of Confounding in Medical Imaging Models

open access: yesMachine Learning and Knowledge Extraction
Machine learning models for medical image analysis are vulnerable to hidden confounders, which can compromise generalization and clinical reliability. Existing detection strategies typically require explicit knowledge or labels of the confounder, which ...
Uma M. Lal-Trehan Estrada   +4 more
doaj   +1 more source

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