Results 81 to 90 of about 1,001,591 (299)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Spatiotemporal models with confounding effects: application on under-five mortality across four sub-Saharan African countries

Frontiers in Public Health
BackgroundDifferent strategies have been developed to minimize under-five mortality (U5M) in sub-Saharan African (sSA) countries; however, it is still a major health concern for children in the region.
Haile Mekonnen Fenta, Haile Mekonnen Fenta, Ding-Geng Chen, Ding-Geng Chen, Temesgen T. Zewotir, Najmeh Nakhaei Rad   +5 more
doaj   +1 more source

Adaptability of High Dimensional Propensity Score Procedure in the Transition from ICD-9 to ICD-10 in the US Healthcare System

Clinical Epidemiology, 2023
Amir Sarayani,1,2 Joshua D Brown,1,2 Christian Hampp,1,3 William T Donahoo,4,5 Almut G Winterstein1,2 1Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL, USA; 2Center for Drug Safety and ...
Sarayani A, Brown JD, Hampp C, Donahoo WT, Winterstein AG   +4 more
doaj  

Propensity Score Methods in Health Technology Assessment: Principles, Extended Applications, and Recent Advances

Frontiers in Pharmacology, 2019
Randomized clinical trials (RCT) are accepted as the gold-standard approaches to measure effects of intervention or treatment on outcomes. They are also the designs of choice for health technology assessment (HTA). Randomization ensures comparability, in
M Sanni Ali, M Sanni Ali, M Sanni Ali, Daniel Prieto-Alhambra, Daniel Prieto-Alhambra, Luciane Cruz Lopes, Dandara Ramos, Nivea Bispo, Maria Y. Ichihara, Maria Y. Ichihara, Julia M. Pescarini, Elizabeth Williamson, Rosemeire L. Fiaccone, Rosemeire L. Fiaccone, Rosemeire L. Fiaccone, Mauricio L. Barreto, Mauricio L. Barreto, Liam Smeeth, Liam Smeeth   +18 more
doaj   +1 more source

Confounding factors for case exclusion.

, 2014
Note: 55 dogs in total were excluded during case filtering because of confounding clinical factors. More than one confounding factor was found in some dogs.Confounding factors for case exclusion.
Connie Chuang (634419), Rebecca A. Csomos (634421), Sirjaut Kaur (634420), Megan A. Ramaker (572040), Susan L. Schaefer (342554), Jason A. Bleedorn (342553), Kevin T. Kroner (634422), Peter Muir (308211)   +7 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Methodological Tutorial Series for Epidemiological Studies: Confounder Selection and Sensitivity Analyses to Unmeasured Confounding From Epidemiological and Statistical Perspectives

Journal of Epidemiology
In observational studies, identifying and adjusting for a sufficient set of confounders is crucial for accurately estimating the causal effect of the exposure on the outcome.
Kosuke Inoue, Kentaro Sakamaki, Sho Komukai, Yuri Ito, Atsushi Goto, Tomohiro Shinozaki   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Confounding [PDF]

, 2001
Bij observationeel onderzoek is het vaak lastig om te weten van welke risicofactor een geconstateerd effect afkomstig is. Vermenging van effect van verschillende risicofactoren is daarvan vaak de oorzaak.
Miranda, E. de, Buitendijk, S.E.
core   +1 more source

Curr Epidemiol Rep [PDF]

Purpose of review:Violence prevention research has enhanced our understanding of individual and community risk and protective factors for aggression and violence.

core