Results 31 to 40 of about 22,198 (205)

Association of congenital Zika syndrome with dental alterations in children with microcephaly

PLoS ONE, 2022
The effects of congenital Zika syndrome (CZS) on the tooth development of infected children are not well known. The aim of this study was to analyze the association of CZS with dental alterations in children with microcephaly seen at a referral hospital ...
Patrícia Nóbrega Gomes, Beatriz Aguiar do Amaral, Isabelita Duarte Azevedo, Haline Cunha de Medeiros Maia, Nivia Maria Rodrigues Arrais, Kenio Costa de Lima   +5 more
doaj  

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Microcephaly in South Brazil: Are cases of Congenital Zika Syndrome increasing in recent years?

Genetics and Molecular Biology
Northeast Brazil was the first region to detect a significant increase in babies born with microcephaly associated with prenatal zika virus infection in 2015.
Anna Pires Terra, Ricardo Rohweder, Silvani Herber, Luciana Friedrich, Maria Teresa Vieira Sanseverino, Catia Favreto, Fernanda Santa Maria, Emilly de Jesus Athayde, Laércio Moreira Cardoso-Júnior, Andrea Cristina Pereira Marinho, Allanamara Pereira Marinho, Tailine Zarpelon, Lavínia Schuler-Faccini   +12 more
doaj   +1 more source

Burden of disease due to microcephaly associated with the Zika virus in Colombia [PDF]

Cadernos de Saúde Pública
In 2015, the Zika virus was introduced in Colombia. The emergence of this arbovirus is a public health challenge for the country, considering the association between the infection and congenital disorders such as microcephaly.
Andrés Felipe Mora-Salamanca, Alexandra Porras-Ramírez, Fernando Pío de la Hoz Restrepo   +2 more
doaj   +2 more sources

Zika-exposed microcephalic neonates exhibit higher degree of inflammatory imbalance in cerebrospinal fluid

Scientific Reports, 2021
Not every neonate with congenital Zika virus (ZIKV) infection (CZI) is born with microcephaly. We compared inflammation mediators in CSF (cerebrospinal fluid obtained from lumbar puncture) between ZIKV-exposed neonates with/without microcephaly (cases ...
Gustavo C. Nascimento-Carvalho, Eduardo C. Nascimento-Carvalho, Clara L. Ramos, Ana-Luisa Vilas-Boas, Otávio A. Moreno-Carvalho, Caian L. Vinhaes, Beatriz Barreto-Duarte, Artur T. L. Queiroz, Bruno B. Andrade, Cristiana M. Nascimento-Carvalho   +9 more
doaj   +1 more source

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source

Ultrasound prediction of Zika virus-associated congenital injury using the profile of fetal growth.

PLoS ONE, 2020
Zika virus (ZIKV) is a mosquito-transmitted flavivirus, recently linked to microcephaly and central nervous system anomalies following infection in pregnancy. Striking findings of disproportionate growth with a smaller than expected head relative to body
Christie L Walker, Noah Ehinger, Brittney Mason, Elizabeth Oler, Marie-Térèse E Little, Eric O Ohuma, Aris T Papageorghiou, Unzila Nayeri, Christine Curry, Kristina M Adams Waldorf   +9 more
doaj   +1 more source

A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2019
Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury.
Hüseyin Anıl Korkmaz, Çağatay Ermiş
doaj   +1 more source

Congenital Zika syndrome: Growth, clinical, and motor development outcomes up to 36 months of age and differences according to microcephaly at birth

International Journal of Infectious Diseases, 2021
Background: Little is known regarding the developmental consequences of congenital Zika syndrome (CZS) without microcephaly at birth. Most previously published clinical series were descriptive and they had small sample sizes. Study design: We conducted a
Tamires Barradas Cavalcante, Marizélia Rodrigues Costa Ribeiro, Patrícia da Silva Sousa, Elaine de Paula Fiod Costa, Maria Teresa Seabra Soares de Brito e Alves, Vanda Maria Ferreira Simões, Rosângela Fernandes Lucena Batista, Eliana Harumi Morioka Takahasi, Gláucio Andrade Amaral, Ricardo Khouri, Maria dos Remédios Freitas Carvalho Branco, Ana Karolina Torres Mendes, Luciana Cavalcante Costa, Marcos Adriano Garcia Campos, Antônio Augusto Moura da Silva   +14 more
doaj   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source