Results 41 to 50 of about 290,347 (229)

Congenital Zika Virus Syndrome: Microcephaly and Orofacial Anomalies

Life, 2023
The progressive reappearance of the Zika virus (ZIKV) infection since October 2013 and its circulation in >70 countries and territories (from French Polynesia to Brazil and other countries in the Americas, with sporadic spread in Europe and the East) has long been reported as a global public health emergency.
Gaetano Scotto, Salvatore Massa, Francesca Spirito, Vincenzina Fazio   +3 more
openaire   +3 more sources

Microcephaly in Neurometabolic Diseases

Children, 2022
Neurometabolic disorders are an important group of diseases that mostly occur in neonates and infants. They are mainly due to the lack or dysfunction of an enzyme or cofactors necessary for a specific biochemical reaction, which leads to a deficiency of ...
Wiktoria Kempińska, Karolina Korta, Magdalena Marchaj, Justyna Paprocka   +3 more
doaj   +1 more source

Altered inhibition and excitation in neocortical circuits in congenital microcephaly [PDF]

Neurobiology of Disease, 2019
Congenital microcephaly is highly associated with intellectual disability. Features of autosomal recessive primary microcephaly subtype 3 (MCPH3) also include hyperactivity and seizures. The disease is caused by biallelic mutations in the Cyclin-dependent kinase 5 regulatory subunit-associated protein 2 gene CDK5RAP2.
Sami Zaqout, Kathrin Blaesius, Yuan-Ju Wu, Stefanie Ott, Nadine Kraemer, Lena-Luise Becker, Marta Rosário, Christian Rosenmund, Ulf Strauss, Angela M. Kaindl   +9 more
openaire   +3 more sources

CHROMOSOMAL ANALYSIS OF MENTALLY RETARDED CHILDREN WITH MICROCEPHALY [PDF]

, 2011
Background: Mental retardation is a common condition with the incidence of 1- 3% of the entire population; about 25% - 50% of them are genetic causes. Chromosomal causes account for up to 28%.
Afadiyanti, Alfi, Rusdi, Wiyosa Waluyan, Putra, Farmaditya Eka   +2 more
core   +1 more source

Zika virus infection and microcephaly: spatial analysis and socio-environmental determinants in a region of high Aedes aegypti infestation in the Central-West Region of Brazil

BMC Infectious Diseases, 2021
Background More than 5 years after the Zika virus (ZIKV) epidemic, Zika infection remains a major concern in regions with high Aedes infestation. The objectives of this study were (i) to identify clusters of ZIKV infection and microcephaly, and/or ...
Patrícia Silva Nunes, Rafael Alves Guimarães, Celina Maria Turchi Martelli, Wayner Vieira de Souza, Marília Dalva Turchi   +4 more
doaj   +1 more source

Variants in CEP135 Cause Congenital Microcephaly and Primary Ciliary Dyskinesia. [PDF]

Pediatr Pulmonol
ABSTRACT Introduction Primary ciliary dyskinesia (PCD), a disorder of motile ciliary dysfunction causing chronic respiratory infections, may also rarely present with aspects of non‐motile ciliary dysfunction, including retinitis, central nervous system malformations, skeletal dysplasia, and sensorineural hearing loss.
Bergman-Sieger A, Turcot MA, Ostrowski LE, Sears PR, Zariwala MA, Bechkir F, Young LR, Shapiro AJ, Parenti MB.   +8 more
europepmc   +2 more sources

Another piece of the Zika puzzle: assessing the associated factors to microcephaly in a systematic review and meta-analysis

BMC Public Health, 2020
Background Although it is known that Zika virus (ZIKV) infection during pregnancy may lead to microcephaly in the fetus, the prognostic factors associated with this tragic disorder remain unclear.
Luciana Guerra Gallo, Jorge Martinez-Cajas, Henry Maia Peixoto, Ana Carolina Esteves da Silva Pereira, Jillian E. Carter, Sandra McKeown, Bruno Schaub, Camila V. Ventura, Giovanny Vinícius Araújo de França, Léo Pomar, Liana O. Ventura, Vivek R. Nerurkar, Wildo Navegantes de Araújo, Maria P. Velez   +13 more
doaj   +1 more source

Nonmicrocephalic Infants with Congenital Zika Syndrome Suspected Only after Neuroimaging Evaluation Compared with Those with Microcephaly at Birth and Postnatally: How Large Is the Zika Virus “Iceberg”? [PDF]

, 2017
Although microcephaly is the most prominent feature of congenital Zika syndrome, a spectrum with less severe cases is starting to be recognized. Our aim was to review neuroimaging of infants to detect cases without microcephaly and compare them with ...
Aragao,, Holanda,, Brainer-Lima,, Tenório,, Valenca,, Travassos,, Castillo,, Sarteschi,, Van Der Linden,, Costello,, Cordeiro,, Serpa,, Petribu,   +12 more
core   +3 more sources

Zika Virus RNA Replication and Persistence in Brain and Placental Tissue

Emerging Infectious Diseases, 2017
Zika virus is causally linked with congenital microcephaly and may be associated with pregnancy loss. However, the mechanisms of Zika virus intrauterine transmission and replication and its tropism and persistence in tissues are poorly understood.
Julu Bhatnagar, Demi B. Rabeneck, Roosecelis B. Martines, Sarah Reagan-Steiner, Yokabed Ermias, Lindsey B.C. Estetter, Tadaki Suzuki, Jana M. Ritter, M. Kelly Keating, Gillian Hale, Joy Gary, Atis Muehlenbachs, Amy J. Lambert, Robert Lanciotti, Titilope Oduyebo, Dana Meaney-Delman, Fernando Bolaños, Edgar Alberto Parra Saad, Wun-Ju Shieh, Sherif Zaki   +19 more
doaj   +1 more source

Association of congenital Zika syndrome with dental alterations in children with microcephaly

PLoS ONE, 2022
The effects of congenital Zika syndrome (CZS) on the tooth development of infected children are not well known. The aim of this study was to analyze the association of CZS with dental alterations in children with microcephaly seen at a referral hospital ...
Patrícia Nóbrega Gomes, Beatriz Aguiar do Amaral, Isabelita Duarte Azevedo, Haline Cunha de Medeiros Maia, Nivia Maria Rodrigues Arrais, Kenio Costa de Lima   +5 more
doaj